Alexey Ruzov

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Associate Professor in Stem Cell Biology

University of Nottingham

United Kingdom

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Dr. Alexey Ruzov is an Associate Professor in Stem Cell Biology at the University of Nottingham, UK. His research interests encompass various aspects of stem cell differentiation, RNA-DNA interactions, and the roles of nucleotides in prebiotic evolution. Recent publications include studies on genome mapping in Escherichia coli, the dynamics of transposable elements during human pluripotent stem cell differentiation, and the implications of single nucleotide polymorphisms on protein stability in anticancer therapeutics.

Recent Grants

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Studying potential interplay between active demethylation and WT1-dependent transcriptional regulation during glial differentiation.

Open Date: 2016-03-31

Close Date: 2019-03-31

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2025

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Collaborators (6)

Ayhan Kocer

Associate Professor

Université Clermont Auvergne

FRANCE

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Oxana Bereshchenko

Associate Professor

University of Perugia

ITALY

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Lorraine Young

Senior Lecturer

University of Nottingham

UNITED KINGDOM

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Julie Cocquet

Université Paris Cité

FRANCE

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Marta Starczak

Nicolaus Copernicus University

POLAND

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Stefano Bruscoli

University of Perugia

ITALY

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Alexey Ruzov

Research Interests

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About

Recent Grants

Articles (15)

Genome Mapping of RNA-DNA Hybrids in Escherichia coli

Transposable element expression and sub-cellular dynamics during hPSC differentiation to endoderm, mesoderm, and ectoderm lineages.

The non-canonical nucleotides and prebiotic evolution

A model for a dual function of N6-methyladenosine in R-loop regulation

Analyzing the Effects of Single Nucleotide Polymorphisms on hnRNPA2/B1 Protein Stability and Function: Insights for Anticancer Therapeutic Design

Effect of Lactobacillus reuteri NCIMB 30351 drops on symptoms of infantile functional gastrointestinal disorders and gut microbiota in early infants: Results from a randomized, placebo-controlled clinical trial

The Functions of N<sup>6</sup>-Methyladenosine in Nuclear RNAs

SWI/SNF complexes as determinants of R-loop metabolism

LINE-1 transcription in round spermatids is associated with accretion of 5-carboxylcytosine in their open reading frames.

Analysis of 5-Carboxylcytosine Distribution Using DNA Immunoprecipitation.

Detection of Low-Abundance DNA Modifications Using Signal Amplification-Based Immunocytochemistry.

Evidence for Noncytosine Epigenetic DNA Modifications in Multicellular Eukaryotes: An Overview.

Modified Forms of Cytosine in Eukaryotes: DNA (De)methylation and Beyond.

N <sup>6</sup>-methyladenosine regulates the stability of RNA:DNA hybrids in human cells

5-formylcytosine and 5-hydroxymethyluracil as surrogate markers of TET2 and SF3B1 mutations in myelodysplastic syndrome, respectively

Collaborators (6)

Ayhan Kocer

Oxana Bereshchenko

Lorraine Young

Julie Cocquet

Marta Starczak

Stefano Bruscoli

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