Alfred Antson

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Professor

University of York

United Kingdom

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About

Professor Alfred Antson is a faculty member at the University of York, UK. His research focuses on viral genome packaging mechanisms and the structural biology of viral proteins. Recent publications include investigations into the helicase activity of human PIF1, the virome dissemination in the Central Arctic, and the structure of various viral motor proteins.

Recent Grants

Grant: Open

Molecular mechanism of genome packaging by dsDNA viruses

Open Date: 2022-08-01

Close Date: 2027-07-31

Grant: Close

Structure and mechanism of nucleic acid-processing machines in viral biogenesis

Open Date: 2017-08-01

Close Date: 2022-08-01

Grant: Close

A regional cryoEM facility at the University of York

Open Date: 2017-08-01

Close Date: 2022-07-31

Grant: Close

Bilateral NSF/BIO-BBSRC: Engineering Tunable Portal Hybrid Nanopores for High-Resolution Sequence Mapping

Open Date: 2016-06-30

Close Date: 2019-06-29

Grant: Close

Opening of a double stranded DNA replication fork by a hexameric helicase

Open Date: 2014-02-01

Close Date: 2017-01-31

Articles (17)

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2025

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2024

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2024

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2024

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2023

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2023

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2022

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2021

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2021

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2021

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2020

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2020

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2020

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2020

Collaborators (11)

Colin Hill

Lecturer/Professor

University College Cork

IRELAND

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Andrey Shkoporov

Professor

University College Cork

IRELAND

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Beibei Wang

University of Oxford

UNITED KINGDOM

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Ping Zhang

University of Oxford

UNITED KINGDOM

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Sarah McDonald

University of Glasgow

UNITED KINGDOM

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Yi Jin

The University of Manchester

UNITED KINGDOM

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Andrey Sysoev

Max Planck Institute of Molecular Physiology

GERMANY

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Mariolina Salio

University of Oxford

UNITED KINGDOM

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Jean-Francois Poissson

Professeur

Université Grenoble Alpes

FRANCE

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Julia Weissenbach

Linnaeus University

SWEDEN

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Herman KH Fung

Assistant Professor

University of Michigan

UNITED STATES

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Alfred Antson

Research Interests

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About

Recent Grants

Articles (17)

Penton blooming, a conserved mechanism of genome delivery used by disparate microviruses

Structural basis for DNA recognition by a viral genome-packaging machine

Surface microlayer-mediated virome dissemination in the Central Arctic

Structure-based discovery of first inhibitors targeting the helicase activity of human PIF1

Viral Genomic DNA Packaging Machinery

Structural atlas of a human gut crassvirus

Insights into a viral motor: the structure of the HK97 packaging termination assembly

Human 14-3-3 Proteins Site-selectively Bind the Mutational Hotspot Region of SARS-CoV-2 Nucleoprotein Modulating its Phosphoregulation

Jorvik: A membrane-containing phage that will likely found a new family within Vinavirales

High-Voltage Biomolecular Sensing Using a Bacteriophage Portal Protein Covalently Immobilized within a Solid-State Nanopore

Octahedral Trifluoromagnesate, an Anomalous Metal Fluoride Species, Stabilizes the Transition State in a Biological Motor

CryoEM structure of the Nipah virus nucleocapsid assembly

The mechanism of SARS-CoV-2 nucleocapsid protein recognition by the human 14-3-3 proteins

Broad and strong memory CD4<sup>+</sup> and CD8<sup>+</sup> T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19.

Molecular basis for the recognition of steroidogenic acute regulatory protein by the 14‐3‐3 protein family

Cryo-EM structure in situ reveals a molecular switch that safeguards virus against genome loss

Diversity and Host Interactions among Virulent and Temperate Baltic Sea Flavobacterium Phages

Collaborators (11)

Colin Hill

Andrey Shkoporov

Beibei Wang

Ping Zhang

Sarah McDonald

Yi Jin

Andrey Sysoev

Mariolina Salio

Jean-Francois Poissson

Julia Weissenbach

Herman KH Fung

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