Alice Cheng

University of California, San Francisco

United States

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Articles (5)

Year:

2023

Year:

2023

Year:

2022

Year:

2021

Year:

2021

Collaborators (4)

Sae-Won Han

Seoul National University

SOUTH KOREA

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Michael Trnka

Associate Adjunct Professor

University of California, San Francisco

UNITED STATES

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Anatoly Urisman

University of California

UNITED STATES

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Pau Castel

Assistant Professor

New York University Grossman School of Medicine

UNITED STATES

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Alice Cheng

Research Interests

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Articles (5)

Destabilizing NF1 variants act in a dominant negative manner through neurofibromin dimerization

RAS-dependent RAF-MAPK hyperactivation by pathogenic RIT1 is a therapeutic target in Noonan syndrome-associated cardiac hypertrophy.

Cross-species analysis of LZTR1 loss-of-function mutants demonstrates dependency to RIT1 orthologs.

RAS interaction with Sin1 is dispensable for mTORC2 assembly and activity

The RAS GTPase RIT1 compromises mitotic fidelity through spindle assembly checkpoint suppression.

Collaborators (4)

Sae-Won Han

Michael Trnka

Anatoly Urisman

Pau Castel

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