Alison Taylor

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University of Leeds

United Kingdom

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Recent Grants

Grant: Close

Defining non-redundant functions of glycogen synthase kinase (GSK)-3 alpha and GSK-3 beta in T cell subsets that control tumour growth

Open Date: 2021-09-30

Close Date: 2024-09-29

Grant: Close

A Novel Pathway that Down-regulates PD-1 Expression for the Treatment of Cancer

Open Date: 2015-07-01

Close Date: 2018-06-30

Articles (6)

Year:

2022

Year:

2022

Year:

2021

Year:

2021

Year:

2020

Year:

2020

Collaborators (1)

Graham Cook

Professor of Molecular and Cellular Immunology

University of Leeds

UNITED KINGDOM

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Alison Taylor

Research Interests

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Recent Grants

Articles (6)

Editorial: Factors determining long term anti-tumor responses to immune checkpoint blockade therapy

Elraglusib (9-ING-41), a selective small-molecule inhibitor of glycogen synthase kinase-3 beta, reduces expression of immune checkpoint molecules PD-1, TIGIT and LAG-3 and enhances CD8+ T cell cytolytic killing of melanoma cells

Tumour cell CD99 regulates transendothelial migration via CDC42 and actin remodelling

Non-redundant activity of GSK-3α and GSK-3β in T cell-mediated tumor rejection

Glycogen synthase kinase 3 (GSK-3) controls T-cell motility and interactions with antigen presenting cells

Small Molecule Inhibition of GSK-3 Specifically Inhibits the Transcription of Inhibitory Co-receptor LAG-3 for Enhanced Anti-tumor Immunity

Collaborators (1)

Graham Cook

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