Alyssa H. Hasty
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Recent Grants
Grant: Close
Novel regulation of insulin receptor by the innate immune system
Open Date: 2017-01-01
Close Date: 2019-12-31
Grant: Close
Novel regulation of insulin receptor by the innate immune system
Open Date: 2017-01-01
Close Date: 2019-12-31
Grant: Close
Turnover of Adipose Tissue Macrophages
Open Date: 2014-07-01
Close Date: 2018-06-30
Grant: Close
Turnover of Adipose Tissue Macrophages
Open Date: 2014-07-01
Close Date: 2018-06-30
Grant: Close
Adipose Tissue Macrophage Iron Metabolism in Obesity
Open Date: 2012-05-01
Close Date: 2015-04-30
Articles (13)
Year:
2024
We generated a new mouse model of complement factor 5 deficiency. This work was prompted by a need for improved transgenic mouse lines of C5, due to off-target gene mutations. We find that loss of C5 worsens glucose tolerance in a sex-dependent manner. Though the mechanisms evoking glucose intolerance are not clear, we are confident this model will be useful in interrogating complement activation in obesity-associated diseases.
Year:
2023
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2023
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2023
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2022
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2022
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2022
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2022
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2022
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2021
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2021
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2020
Year:
2020
Collaborators (5)
Lorraine Ware
Vanderbilt University Medical Center
Vern Kerchberger
Assistant Professor of Medicine
Vanderbilt University Medical Center
Nathan Winn
Assistant Professor
Vanderbilt University Medical Center
Rafael Arrojo e Drigo
Assistant Professor
Vanderbilt University
Heather Caslin
Assistant Professor
University of Houston
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