Amanda Dann

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Assistant Professor

University of Texas Southwestern Medical Center

United States

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About

Amanda Dann is an Assistant Professor at The University of Texas Southwestern Medical Center, USA. Her research primarily focuses on pancreatic cancer, examining the metabolic alterations and survival outcomes associated with various therapeutic approaches. Recent publications highlight her work on the role of nucleotide metabolism, surgical resection outcomes, and the impact of interferon signaling in cancer treatment.

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NIH T32 Digestive Disease Research GI Training Grant

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Articles (7)

Year:

2023

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2022

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2021

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2021

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2021

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2021

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2020

Collaborators (2)

Jason Link

University of California, Los Angeles

UNITED STATES

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Caius Radu

Professor

UCLA

UNITED STATES

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Amanda Dann

Research Interests

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Recent Grants

Articles (7)

Higher Numbers of Examined Lymph Nodes Are Associated with Increased Survival in Resected, Treatment-Naïve, Node-Positive Esophageal, Gastric, Pancreatic, and Colon Cancers.

Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cells.

NAD<sup>+</sup> depletion by type I interferon signaling sensitizes pancreatic cancer cells to NAMPT inhibition

Author Correction: Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring.

STING-driven interferon signaling triggers metabolic alterations in pancreas cancer cells visualized by [<sup>18</sup>F]FLT PET imaging.

Surgical resection of high-grade nonfunctional pancreatic neuroendocrine carcinoma is associated with improved survival.

Histone deacetylase inhibition is synthetically lethal with arginine deprivation in pancreatic cancers with low argininosuccinate synthetase 1 expression

Collaborators (2)

Jason Link

Caius Radu

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