Amber Smith

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Assistant Professor

University of Tennessee Health Science Center

United States

Research Interests

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About

Amber Smith is an Assistant Professor at the University of Tennessee Health Science Center in the United States. Her research focuses on statistical modeling and immune responses in the context of infectious diseases, particularly SARS-CoV-2 and influenza. Recent publications include studies on serological surveillance, immune kinetics, and the relationship between host genetics and disease severity.

Recent Grants

Grant: Open

Virtual Patient Cohorts to Illuminate Immunologic Drivers of Influenza Severity

Open Date: 2022-06-01

Close Date: 2027-05-31

Grant: Close

Predictive Modeling of Influenza-Pneumococcal Coinfection

Open Date: 2018-07-01

Close Date: 2023-06-30

Grant: Close

Quantifying and Validating Immune Response Dynamics for Influenza and Viral-Bacterial Pneumonias

Open Date: 2016-08-18

Close Date: 2017-07-31

Grant: Close

Quantifying and Validating Immune Response Dynamics for Influenza and Viral-Bacterial Pneumonias

Open Date: 2016-08-18

Close Date: 2019-07-31

Grant: Close

Bacterial virulence factors contributing to virus-associated pneumonias

Open Date: 2012-07-01

Close Date: 2017-06-30

Articles (17)

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2025

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2023

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2021

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2021

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2021

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2021

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2020

Collaborators (15)

Morgan Craig

Université de Montréal

CANADA

Amber Smith

Research Interests

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About

Recent Grants

Articles (17)

The Intersection of SARS-CoV-2 and Diabetes

The impact of statistical adjustment for assay performance on inferences from SARS-CoV-2 serological surveillance studies

Quantitatively mapping immune control during influenza

Decoding immune kinetics: unveiling secrets using custom-built mathematical models

Toward mechanistic medical digital twins: some use cases in immunology

Forum on immune digital twins: a meeting report

BioModels’ Model of the Year 2023

Host response to influenza infections in human blood: association of influenza severity with host genetics and transcriptomic response

Dissecting Phenotype from Genotype with Clinical Isolates of SARS-CoV-2 First Wave Variants

How Interactions during Viral–Viral Coinfection Can Shape Infection Kinetics

Erratum: Time to revisit the endpoint dilution assay and to replace the TCID<sub>50</sub> as a measure of a virus sample’s infection concentration (PLoS Comput Biol (2021) 17:10 (e1009480) DOI: 10.1371/journal.pcbi.1009480)

Increased virus dissemination leads to enhanced lung injury but not inflammation during influenza-associated secondary bacterial infection

COVID-19 virtual patient cohort suggests immune mechanisms driving disease outcomes

Time to revisit the endpoint dilution assay and to replace the TCID50 as a measure of a virus sample’s infection concentration

Quantifying dose-, strain-, and tissue-specific kinetics of parainfluenza virus infection

Dynamically linking influenza virus infection kinetics, lung injury, inflammation, and disease severity

Extracellular Vesicles in Viral Replication and Pathogenesis and Their Potential Role in Therapeutic Intervention

Collaborators (15)

Morgan Craig

Luis Fonseca

Amali Samarasinghe

Intawat Nookaew

Penelope Morel

Colleen Jonsson

Courtney Davis

Crystal Burke

sunitha kodidela

Adrianne Jenner

Micholas Smith

Catherine Beauchemin

Xueyuan Cao

Michelle Aranha

Briana Spruill-Harrell

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