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Amit Kumawat

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Ricercatore

Ospedale San Raffaele

Italy

Research Interests

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Professors in Italy Professors in Biochemistry Biochemistry professors in Italy

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Grant: Close

Tumor-specific targeting of RhoGDI upregulation and downregulation via in silico approaches

Open Date: 2024-01-01

Close Date: 2025-12-31

Articles (12)

Year:

2026

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2026

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2026

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2026

Year:

2025

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2025

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2025

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2025

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2024

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2024

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2024

Year:

2023

Collaborators (10)

Paolo Gabrieli

Professore Associato

University of Milan

ITALY

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Ruth Nussinov

Professor, Senior Scientist

National Institutes of Health

UNITED STATES

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Stefano Ricagno

Full Professor

University of Milan

ITALY

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Suman Chakrabarty

Professor

S. N. Bose National Centre for Basic Sciences

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Antonio Chaves-Sanjuan

Ricercatori

University of Milan

ITALY

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simona masiero

Full Professor

Università di Milano

ITALY

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LOUISE JANE GOURLAY

Assistant Professor in Biochemistry

Università degli Studi di Torino

ITALY

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Stefan T Arold

Associate Dean, BESE

King Abdullah University of Science and Technology

SAUDI ARABIA

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Walter Rocchia

Senior Scientist

Istituto Italiano di Tecnologia

ITALY

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Maria Maddalena Cavalluzzi

University of Bari Aldo Moro

ITALY

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Amit Kumawat

Research Interests

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Articles (12)

Phosphorylation induces altered protonation states and allosterically regulates Rac1–RhoGDI complex

Targeting the histone‐fold dimerization interface of oocyst rupture proteins from <i>Plasmodium berghei</i> for antimalarial inhibitor discovery

SCRIB inhibits PP1 phosphatase activity without blocking or structurally altering its active site

Mapping the Binding Landscape of Allosteric Inhibitor G6PDi-1 on Human G6PD

Dimer dissociation and aggregation hot-spot exposure synergistically accelerate light chain variable domain aggregation associated with AL amyloidosis

Structural basis of Nuclear Factor 1-X DNA recognition provides prototypic insight into the NFI family

Molecular insights into the rescue mechanism of an HERG activator against severe LQT2 mutations

The Conformational Landscape of AlphaFold2-Predicted Amyloidogenic Light Chains and Their Correlation With VL Domain Mutations and Aggregation Propensity

Elucidating the microscopic origin of observed anti-correlation between the protein-protein and protein-water interaction energies

Molecular mechanism of regulation of RhoA GTPase by phosphorylation of RhoGDI

Pathogenic <i>G6PD</i> variants: Different clinical pictures arise from different missense mutations in the same codon

hERG stereoselective modulation by mexiletine‐derived ureas: Molecular docking study, synthesis, and biological evaluation

Collaborators (10)

Paolo Gabrieli

Ruth Nussinov

Stefano Ricagno

Suman Chakrabarty

Antonio Chaves-Sanjuan

simona masiero

LOUISE JANE GOURLAY

Stefan T Arold

Walter Rocchia

Maria Maddalena Cavalluzzi

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