Amy Buck

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Professor of RNA & Infection Biology

University of Edinburgh

United Kingdom

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Amy Buck is a Professor of RNA & Infection Biology at the University of Edinburgh, located in the United Kingdom. Her research primarily focuses on the roles of extracellular RNAs and vesicles in various biological processes, including their interactions in host-pathogen dynamics. Recent publications examine themes such as RNA transfer, the involvement of microRNAs in immune regulation, and the characterization of extracellular vesicles in malaria and parasitic nematodes.

Recent Grants

Grant: Close

Rapid diagnosis of onchocerciasis using urinary biomarkers

Open Date: 2017-03-01

Close Date: 2019-02-28

Grant: Close

microRNA diagnostics of filarial infection

Open Date: 2016-05-01

Close Date: 2018-01-31

Grant: Close

Extracellular RNAi pathway as a mechanism of parasite-host communication

Open Date: 2014-09-01

Close Date: 2018-09-01

Grant: Close

Tipping the balance: pathogen manipulation of microRNA regulatory pathways.

Open Date: 2012-02-01

Close Date: 2017-01-31

Grant: Close

Systematic analysis of antiviral microRNA function

Open Date: 2011-12-01

Close Date: 2015-05-30

Articles (12)

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2025

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2025

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2024

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2024

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2024

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2024

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2022

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2021

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2020

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2020

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2020

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2020

Collaborators (5)

Cei Abreu-Goodger

Reader in Bioinformatics

University of Edinburgh

UNITED KINGDOM

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Frances Blow

University of Glasgow

UNITED KINGDOM

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Neeraj Dhaun

University of Edinburgh

UNITED KINGDOM

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Esther N. M. Nolte-‘t Hoen

Utrecht University

NETHERLANDS

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Robert Hunter

Clinical Lecturer

University of Edinburgh

UNITED KINGDOM

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Amy Buck

Research Interests

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About

Recent Grants

Articles (12)

SLAMseq reveals potential transfer of RNA from liver to kidney in the mouse

mGem: Guides or triggers? Extracellular RNAs beyond vesicular miRNAs

Intracellular localisation and extracellular release of Y RNA and Y RNA binding proteins

SID-2 is a conserved extracellular vesicle protein that is not associated with environmental RNAi in parasitic nematodes

RNA–RNA interactions between respiratory syncytial virus and miR-26 and miR-27 are associated with regulation of cell cycle and antiviral immunity

miR-7 is recruited to the high molecular weight RNA-induced silencing complex in CD8+T cells upon activation and suppresses IL-2 signaling

Extracellular vesicles from malaria‐infected red blood cells: not all are secreted equal

MicroRNAs and extracellular vesicles in the gut: new host modulators of the microbiome?

Development of caecaloids to study host-pathogen interactions: new insights into immunoregulatory functions of Trichuris muris extracellular vesicles in the caecum.

Extracellular vesicles from Heligmosomoides bakeri and Trichuris muris contain distinct microRNA families and small RNAs that could underpin different functions in the host.

Whole blood profiling of T-cell derived miRNA allows the development of prognostic models in inflammatory bowel disease.

Disentangling sRNA-Seq data to study RNA communication between species

Collaborators (5)

Cei Abreu-Goodger

Frances Blow

Neeraj Dhaun

Esther N. M. Nolte-‘t Hoen

Robert Hunter

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