Amy Stiegler

Yale University

United States

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Articles (8)

Year:

2023

Year:

2023

Year:

2022

Year:

2022

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2022

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2021

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2020

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2020

Collaborators (2)

Struan Grant

Professor of Genetics and Pediatrics

University of Pennsylvania

UNITED STATES

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Sheng Chih Jin

Assistant Professor

Washington University School of Medicine

UNITED STATES

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Amy Stiegler

Research Interests

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Articles (8)

Diverse p120RasGAP interactions with doubly phosphorylated partners EphB4, p190RhoGAP, and Dok1

De novo variants implicate chromatin modification, transcriptional regulation, and retinoic acid signaling in syndromic craniosynostosis.

De novo mutations in the BMP signaling pathway in lambdoid craniosynostosis.

Tandem engagement of phosphotyrosines by the dual SH2 domains of p120RasGAP.

SH3 domain regulation of RhoGAP activity: Crosstalk between p120RasGAP and DLC1 RhoGAP

Constrained chromatin accessibility in PU.1-mutated agammaglobulinemia patients.

The pseudoGTPase group of pseudoenzymes.

The GTPase-activating protein p120RasGAP has an evolutionarily conserved "FLVR-unique" SH2 domain.

Collaborators (2)

Struan Grant

Sheng Chih Jin

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