Ana Cristina Rego

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Associate Professor with 'Agregação'

Faculty of Medicine, University of Coimbra

Portugal

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About

Ana Cristina Rego is an Associate Professor with 'Agregação' at the Faculty of Medicine, University of Coimbra. Her research primarily focuses on mitochondrial dysfunction, synaptic signaling, and their implications in neurodegenerative diseases such as Alzheimer's disease and Huntington's disease. Recent publications highlight her work on the mechanisms linking amyloid-beta peptides to cellular signaling pathways and the impact of mitochondrial changes in various disease models.

Recent Grants

Grant: Close

Examining Fyn/Src in Huntington's disease cell models

Open Date: 2021-11-01

Close Date: 2022-10-01

Grant: Close

Exploring mitochondrial (dys)function and redox changes in type-2 diabetes mellitus and periodontitis patients-derived blood cells

Open Date: 2019-10-01

Close Date: 2020-09-30

Grant: Close

Exploring striatal postsynaptic SAPAP3 in Huntington’s disease

Open Date: 2018-10-01

Close Date: 2019-09-01

Grant: Close

Transcriptional activity modulation in Alzheimer's disease by inhibitors of histone deacetylases

Open Date: 2018-07-01

Close Date: 2021-06-01

Grant: Close

Transcriptional activity modulation in Alzheimer's disease by inhibitors of histone deacetylases

Open Date: 2018-07-01

Close Date: 2021-06-01

Articles (13)

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2024

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2023

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2023

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2023

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2023

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2021

Collaborators (6)

Sandra M Cardoso

Assistant Professor

Universidade do Porto Faculdade de Medicina

PORTUGAL

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Isabel Baptista

Assitant Professor

Universidade do Porto Faculdade de Medicina

PORTUGAL

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Michael R. Hayden

The University of British Columbia

CANADA

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Cristina Januário

University of Coimbra

PORTUGAL

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Ildete Ferreira

PORTUGAL

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Carla Lopes

PORTUGAL

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Ana Cristina Rego

Research Interests

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About

Recent Grants

Articles (13)

Linking activation of synaptic NMDA receptors‐induced CREB signaling to brief exposure of cortical neurons to oligomeric amyloid‐beta peptide

Mitochondrial and Redox Changes in Periodontitis and Type 2 Diabetes Human Blood Mononuclear Cells

Reduction of class I histone deacetylases ameliorates ER‐mitochondria cross‐talk in Alzheimer's disease

Uncovering the Early Events Associated with Oligomeric Aβ-Induced Src Activation

Apoe4 and Alzheimer’s Disease Pathogenesis—Mitochondrial Deregulation and Targeted Therapeutic Strategies

Restoration of c-Src/Fyn Proteins Rescues Mitochondrial Dysfunction in Huntington's Disease

Mitochondrial Dysfunction and Decreased Cytochrome c in Cell and Animal Models of Machado–Joseph Disease

Mitochondrial Dysfunction and Decreased Cytochrome c in Cell and Animal Models of Machado-Joseph Disease

Restored Fyn Levels in Huntington’s Disease Contributes to Enhanced Synaptic GluN2B-Composed NMDA Receptors and CREB Activity

Mitochondrial and redox modifications in early stages of Huntington's disease

Mitochondrial function and dynamics in neural stem cells and neurogenesis: Implications for neurodegenerative diseases

Simultaneous Alteration of the Circadian Variation of Memory, Hippocampal Synaptic Plasticity, and Metabolism in a Triple Transgenic Mouse Model of Alzheimer’s Disease

Boldine Attenuates Synaptic Failure and Mitochondrial Deregulation in Cellular Models of Alzheimer’s Disease

Collaborators (6)

Sandra M Cardoso

Isabel Baptista

Michael R. Hayden

Cristina Januário

Ildete Ferreira

Carla Lopes

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