Ana Isabel Rodriguez Perez

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Associate Professor

Universidade de Santiago de Compostela Facultade de Medicina e Odontoloxía

Spain

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Ana Isabel Rodriguez Perez is an Associate Professor at Universidade de Santiago de Compostela Facultade de Medicina e Odontoloxía in Spain. Her research focuses on neurodegenerative diseases, particularly Alzheimer's and Parkinson's, with recent publications exploring biomarkers, immune responses, and neuronal signaling mechanisms. She is actively involved in studying the interactions within the renin-angiotensin system and its implications in neurobiology and metabolic disorders.

Recent Grants

Grant: Close

SÍNDROME METABÓLICO Y RIESGO DE ENFERMEDAD DE PARKINSON: ESTUDIO EXPERIMENTAL Y CLÍNICO DE LOS MECANISMOS IMPLICADOS

Open Date: 2021-01-01

Close Date: 2023-12-01

Grant: Close

Clarificación del efecto beneficioso o perjudicial de los tratamientos con Sartanes, IECAS e ibuprofeno sobre la vulnerabilidad a la infección y el agravamiento de la enfermedad Covid-19

Open Date: 2020-11-01

Close Date: 2022-04-01

Grant: Close

Estudio experimental y clínico para identificación de marcadores de mecanismos de progresión de la Enfermedad de Parkinson y posibles dianas terapéuticas para neuroprotección

Open Date: 2018-01-01

Close Date: 2020-12-01

Articles (20)

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2021

Collaborators (14)

Maria Campos-Magdaleno

Professor

Universidade de Santiago de Compostela

SPAIN

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Jorge Rodríguez Castro

Universidade de Santiago de Compostela

SPAIN

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Rita Valenzuela Limiñana

Universidade de Santiago de Compostela

SPAIN

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Ana Muñoz

Universidade de Santiago de Compostela

SPAIN

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MANUEL SARMIENTO SOTO

Lecturer

Universidad de Sevilla

SPAIN

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Universidade de Santiago de Compostela

SPAIN

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Antonio Domínguez Meijide

Universidade de Santiago de Compostela

SPAIN

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Jannette Rodriguez-Pallares

Associate Professor

Universidade de Santiago de Compostela

SPAIN

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Miguel Ángel Rivas-Fernández

Universidade de Santiago de Compostela

SPAIN

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Ana Isabel Rodriguez Perez

Research Interests

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About

Recent Grants

Articles (20)

Plasma and neurostructural biomarkers in the clinical-biological characterization of early stages of the Alzheimer's disease continuum: findings from the Compostela Aging Study

Renin–Angiotensin System Autoantibody Network in Parkinson’s Disease Patients

Angiotensin type 1 receptor activation promotes neuronal and glial alpha-synuclein aggregation and transmission

Non-HLA angiotensin-type-1 receptor autoantibodies mediate the long-term loss of grafted neurons in Parkinson’s disease models

The role of the brain renin-angiotensin system in Parkinson´s disease

Biodistribution and pharmacokinetics of [89Zr]-anti-VEGF mAbs using PET in glioblastoma rat models

Inflammatory bowel disease induces pathological α‐synuclein aggregation in the human gut and brain

Cannabinoid regulation of angiotensin II-induced calcium signaling in striatal neurons

Interactions between Angiotensin Type-1 Antagonists, Statins, and ROCK Inhibitors in a Rat Model of L-DOPA-Induced Dyskinesia

The cannabinoid CB<sub>1</sub> receptor interacts with the angiotensin AT<sub>2</sub> receptor. Overexpression of AT<sub>2</sub>-CB<sub>1</sub> receptor heteromers in the striatum of 6-hydroxydopamine hemilesioned rats.

Extracellular Vesicles and Their Renin–Angiotensin Cargo as a Link between Metabolic Syndrome and Parkinson’s Disease

Boolean analysis shows a high proportion of dopamine D<sub>2</sub> receptors interacting with adenosine A<sub>2A</sub> receptors in striatal medium spiny neurons of mouse and non-human primate models of Parkinson's disease.

Microglial angiotensin type 2 receptors mediate sex‐specific expression of inflammatory cytokines independently of circulating estrogen

AT1 receptor autoantibodies mediate effects of metabolic syndrome on dopaminergic vulnerability.

Angiotensin type-1 receptor and ACE2 autoantibodies in Parkinson´s disease.

Angiotensin System Autoantibodies Correlate With Routine Prognostic Indicators for COVID-19 Severity.

Drugs Modulating Renin-Angiotensin System in COVID-19 Treatment

Angiotensin Type-1 Receptor Inhibition Reduces NLRP3 Inflammasome Upregulation Induced by Aging and Neurodegeneration in the Substantia Nigra of Male Rodents and Primary Mesencephalic Cultures.

Parkinson’s disease and diabetes mellitus: common mechanisms and treatment repurposing

NRF2 Activation and Downstream Effects: Focus on Parkinson’s Disease and Brain Angiotensin

Collaborators (14)

Maria Campos-Magdaleno

Jorge Rodríguez Castro

Rita Valenzuela Limiñana

Ana Muñoz

MANUEL SARMIENTO SOTO

María García Garrote

David Rey-Bretal

Santiago Galdo-Alvarez

Jose Luis Labandeira-Garcia

Montserrat Zurrón

Anxo Vidal

Antonio Domínguez Meijide

Jannette Rodriguez-Pallares

Miguel Ángel Rivas-Fernández

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