Andre J. van Wijnen

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University of Vermont

United States

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Professor Andre J. van Wijnen is a faculty member at the University of Vermont, USA. His research focuses on dynamic strain mechanisms, obesity-related mitochondrial dysfunction, and osteoarthritis pathology. Recent publications examine the effects of cellular environments on stem cell behavior and the role of vitamin C in bone health.

Recent Grants

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Molecular Control of Bone Formation

Open Date: 2002-07-01

Close Date: 2022-08-31

Articles (19)

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Collaborators (9)

Johannes van Leeuwen

Erasmus University Rotterdam

NETHERLANDS

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Randip Bindra

Professor

Griffith University

AUSTRALIA

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Yolande F. M. Ramos

Assistant Professor

Leiden University Medical Center

NETHERLANDS

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Hee-Jeong Im

University of Chicago

UNITED STATES

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Bram van der Eerden

Erasmus University Rotterdam

NETHERLANDS

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jeroen van de peppel

Erasmus University Rotterdam

NETHERLANDS

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Janine Post

University of Twente

NETHERLANDS

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Kannan Govindaraj

University of Twente

NETHERLANDS

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Gunes Uzer

Associate Professor

Boise State University

UNITED STATES

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Andre J. van Wijnen

Research Interests

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Recent Grants

Articles (19)

Osmolarity‐Induced Altered Intracellular Molecular Crowding Drives Osteoarthritis Pathology

Dynamic strain and β-catenin mediated suppression of interferon responsive genes in quiescent mesenchymal stromal/stem cells

Obesity-driven mitochondrial dysfunction in human adipose tissue-derived mesenchymal stem/stromal cells involves epigenetic changes

Osmolarity-Induced Altered Intracellular Molecular Crowding Drives Osteoarthritis Pathology

AdipoRon reduces TGFβ1-mediated collagen deposition in vitro and alleviates knee stiffness in vivo

Cellular Enhancement of Frozen Meniscus Allograft Combining Native Meniscus and Mesenchymal Stromal Cell Injections

Loss of PKC8/Prkcd prevents cartilage degeneration in joints but exacerbates hyperalgesia in an experimental osteoarthritis mouse model

Serotonin Transporter (5-Hydroxytryptamine Transporter, SERT, SLC6A4) and Sodium-dependent Reuptake Inhibitors as Modulators of Pain Behaviors and Analgesic Responses

The lysine methyltransferases SET and MYND domain containing 2 (Smyd2) and Enhancer of Zeste 2 (Ezh2) co-regulate osteoblast proliferation and mineralization

Inhibition of Ezh2 redistributes bivalent domains within transcriptional regulators associated with WNT and Hedgehog pathways in osteoblasts

Vitamin C Deficiency Deteriorates Bone Microarchitecture and Mineralization in a Sex‐Specific Manner in Adult Mice

Next-Generation Bone Stimulation: Doubling Down on Bone Anabolics

DNA Variation in Spinal Pathologies: Genetics Running Down the Spine

Opiate Antagonists for Chronic Pain: A Review on the Benefits of Low-Dose Naltrexone in Arthritis versus Non-Arthritic Diseases

BMP2 and GDF5 for Compartmentalized Regeneration of the Scapholunate Ligament

Vitamin C Deficiency Deteriorates Bone Microarchitecture and Mineralization in a Sex-Specific Manner in Adult Mice

Architectural control of mesenchymal stem cell phenotype through nuclear actin

Biomedical Applications of Microfluidic Devices: A Review

<i>Lactobacillus acidophilus</i> Mitigates Osteoarthritis-Associated Pain, Cartilage Disintegration and Gut Microbiota Dysbiosis in an Experimental Murine OA Model

Collaborators (9)

Johannes van Leeuwen

Randip Bindra

Yolande F. M. Ramos

Hee-Jeong Im

Bram van der Eerden

jeroen van de peppel

Janine Post

Kannan Govindaraj

Gunes Uzer

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