Andrea BALLABIO

PROFESSOR

Baylor College of Medicine

United States

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Andrea Ballabio is a Professor at Baylor College of Medicine in the United States. His research focuses on the molecular mechanisms underpinning lysosomal function, particularly the regulation of TFEB and mTORC1, and their implications in various diseases such as liver cancer and cystogenesis. Recent publications explore topics like autophagy, RagGTPases, and dynamic regulation of TFEB nuclear shuttling.

Articles (15)

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2025

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2025

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2025

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2025

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2025

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2023

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2021

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2021

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2021

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2020

Collaborators (7)

Gian Maria Fimia

Full Professor

Sapienza University of Rome

ITALY

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Michele Azzolini

Karolinska Institutet

SWEDEN

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Francesco Cecconi

Head of the Cell Stress and Survival Unit (CSS)

DENMARK

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Celeste Karch

Associate Professor

Washington University in St. Louis

UNITED STATES

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giancarlo parenti

Full Professor

Università degli Studi di Napoli Federico II

ITALY

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Nunzia Pastore

Associate Professor

Università degli Studi di Napoli Federico II

ITALY

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Marco Schiavone

Assistant Professor in Applied Biology

University of Brescia

ITALY

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Andrea BALLABIO

Research Interests

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About

Articles (15)

Folliculin depletion results in liver cell damage and cholangiocarcinoma through MiT/TFE activation

ATG conjugation–dependent/independent mechanisms underlie lysosomal stress–induced TFEB regulation

Structural basis for mTORC1 activation on the lysosomal membrane

Folliculin Deletion in the Mouse Kidney Results in Cystogenesis of the Loops of Henle via Aberrant TFEB Activation

Investigation of dynamic regulation of TFEB nuclear shuttling by microfluidics and quantitative modelling

Ragopathies and the rising influence of RagGTPases on human diseases

Structure of the lysosomal mTORC1–TFEB–Rag–Ragulator megacomplex

Loss of Hepatic Transcription Factor EB Attenuates Alcohol-Associated Liver Carcinogenesis

Multiple Mechanisms Converging on Transcription Factor EB Activation by the Natural Phenol Pterostilbene

A gene toolbox for monitoring autophagy transcription

Autophagy in major human diseases

TFEB regulates lysosomal exocytosis of tau and its loss of function exacerbates tau pathology and spreading

TFEB deficiency attenuates mitochondrial degradation upon brown adipose tissue whitening at thermoneutrality

The rapidly evolving view of lysosomal storage diseases

Lysosomes as dynamic regulators of cell and organismal homeostasis

Collaborators (7)

Gian Maria Fimia

Michele Azzolini

Francesco Cecconi

Celeste Karch

giancarlo parenti

Nunzia Pastore

Marco Schiavone

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