ANDREA MALASPINA

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Professor of Neurology

United Kingdom

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About

Professor Andrea Malaspina is a faculty member in the Department of Neurology at University College London Hospitals (UCLH). His research primarily focuses on amyotrophic lateral sclerosis (ALS), exploring areas such as biomarkers, neuroinflammation, and the efficacy of new treatment approaches. He has contributed significantly to recent studies on the metabolic factors in ALS and methods for disease progression assessment. Professor Malaspina is based in the United Kingdom.

Recent Grants

Grant: Close

United to end MND (U2EM)

Open Date: 2022-10-01

Close Date: 2024-03-01

Grant: Close

Evaluation Of Triumeq As A Treatment For Amyotrophic Lateral Sclerosis

Open Date: 2022-01-01

Close Date: 2025-01-01

Grant: Close

Integrative bioinformatics analysis of fluid-tissue proteomics to develop an ALS predictive model for biomarkers and therapeutic targets discovery

Open Date: 2021-07-01

Close Date: 2025-06-01

Grant: Close

Immunoreactivity to neurofilaments: therapeutics and biomarkers for ALS

Open Date: 2019-11-01

Close Date: 2023-12-01

Grant: Close

Multi-Center ALS Biomarker Validation Study - NIH 2019 U01 NS

Open Date: 2018-01-01

Close Date: 2024-01-01

Articles (20)

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Collaborators (14)

Pamela Shaw

University of Sheffield

UNITED KINGDOM

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Tim Chataway

Flinders University

AUSTRALIA

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Sian Henson

Professor of Immunology

Queen Mary University of London

UNITED KINGDOM

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Peter Munch Andersen

Professor of Neurology (67% of time)

Umea University

SWEDEN

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Carolyn Young

Professor of clinical neurology

University of Liverpool

UNITED KINGDOM

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Claudio Mauro

University of Birmingham

UNITED KINGDOM

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Jason Warren

University College London

UNITED KINGDOM

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Jakub Scaber

University of Oxford

UNITED KINGDOM

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Mary-Louise Rogers

Flinders University

AUSTRALIA

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Pietro Fratta

University College London

UNITED KINGDOM

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John Thornton

University College London

UNITED KINGDOM

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Caroline A McHutchison

Lecturer in Psychology

University of Stirling

UNITED KINGDOM

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Beben Benyamin

University of South Australia

AUSTRALIA

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Ping Yip

Non-Clinical Lecturer in Neuroscience

Queen Mary University of London

UNITED KINGDOM

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ANDREA MALASPINA

Research Interests

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About

Recent Grants

Articles (20)

Skeletal Muscle Biomarkers of Amyotrophic Lateral Sclerosis: A Large‐Scale, Multi‐Cohort Proteomic Study

The metabolic intersection between immunosenescence and neuroinflammation in amyotrophic lateral sclerosis

Determinants and progression of stigma in amyotrophic lateral sclerosis/motor neuron disease

Efficacy and safety of low-dose IL-2 as an add-on therapy to riluzole (MIROCALS): a phase 2b, double-blind, randomised, placebo-controlled trial

Evaluating finger-prick blood collection for remote quantification of neurofilament light in neurological diseases

Glutathione oxidation in cerebrospinal fluid as a biomarker of oxidative stress in amyotrophic lateral sclerosis

Moving past NfL? Multibiomarker models for ALS prognosis and stratification

Moving past NfL? Multibiomarker models for ALS prognosis and stratification

Muscle MRI quantifies disease progression in amyotrophic lateral sclerosis

Lipid-mediated resolution of inflammation and survival in amyotrophic lateral sclerosis

Senescent-like Blood Lymphocytes and Disease Progression in Amyotrophic Lateral Sclerosis

microRNA-based predictor for diagnosis of frontotemporal dementia

Urinary neopterin: A novel biomarker of disease progression in amyotrophic lateral sclerosis

Multicentre appraisal of amyotrophic lateral sclerosis biofluid biomarkers shows primacy of blood neurofilament light chain.

The Expression of Active CD11b Monocytes in Blood and Disease Progression in Amyotrophic Lateral Sclerosis

Mild motor impairment as prodromal state in amyotrophic lateral sclerosis: a new diagnostic entity

Development of a sensitive trial-ready poly(GP) CSF biomarker assay for <i>C9orf72</i>-associated frontotemporal dementia and amyotrophic lateral sclerosis

Circulating miR-181 is a prognostic biomarker for amyotrophic lateral sclerosis

Humoral response to neurofilaments and dipeptide repeats in ALS progression

Amyotrophic lateral sclerosis transcriptomics reveals immunological effects of low-dose interleukin-2

Collaborators (14)

Pamela Shaw

Tim Chataway

Sian Henson

Peter Munch Andersen

Carolyn Young

Claudio Mauro

Jason Warren

Jakub Scaber

Mary-Louise Rogers

Pietro Fratta

John Thornton

Caroline A McHutchison

Beben Benyamin

Ping Yip

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