Andrea Mattevi

Full Professor

Università degli Studi di Pavia

Italy

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About

Andrea Mattevi is a Full Professor at Università degli Studi di Pavia, Italy. His research expertise lies in the structural and mechanistic characterization of enzymes, particularly flavin-dependent monooxygenases and oxidases, as well as biochemical and structural insights into various biocatalytic processes. Recent work includes studies on the biosynthesis of natural products and the evolution of drug-metabolizing enzymes.

Articles (19)

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2025

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Collaborators (5)

Ivana Maric

University of Groningen

NETHERLANDS

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Arthur Ram

Professor Fungal Genetics and Biotechnology

Leiden University

NETHERLANDS

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Marco Fraaije

full professor

University of Groningen

NETHERLANDS

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Lígia O. Martins

Associate Professor

Universidade de Aveiro

PORTUGAL

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Eduardo Pinho Melo

Associate Professor

Universidade do Algarve

PORTUGAL

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Andrea Mattevi

Research Interests

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About

Articles (19)

Structural and Mechanistic Characterization of the Flavin-Dependent Monooxygenase and Oxidase Involved in Sorbicillinoid Biosynthesis

Dehydrogenase versus Oxidase Function: The Interplay between Substrate Binding and Flavin Microenvironment

Biochemical and structural insights into pinoresinol hydroxylase from Pseudomonas sp

Discovery and biochemical characterization of thermostable glycerol oxidases

Biosynthetic Strategies of Berberine Bridge Enzyme-like Flavoprotein Oxidases toward Structural Diversification in Natural Product Biosynthesis

Structure, mechanism, and evolution of the last step in vitamin C biosynthesis

In vitro construction of the COQ metabolon unveils the molecular determinants of coenzyme Q biosynthesis

Evolution, structure, and drug-metabolizing activity of mammalian prenylcysteine oxidases

Rationally Guided Improvement of NOV1 Dioxygenase for the Conversion of Lignin-Derived Isoeugenol to Vanillin

A biosynthetic aspartate N-hydroxylase performs successive oxidations by holding intermediates at a site away from the catalytic center

Structure elucidation and characterization of patulin synthase, insights into the formation of a fungal mycotoxin

Evolution of enzyme functionality in the flavin-containing monooxygenases

Structural Elucidation and Engineering of a Bacterial Carbohydrate Oxidase

Impact of ancestral sequence reconstruction on mechanistic and structural enzymology

One-Pot Biocatalytic Synthesis of rac-Syringaresinol from a Lignin-Derived Phenol

Structure- and computational-aided engineering of an oxidase to produce isoeugenol from a lignin-derived compound

How evolution dismantles and reassembles multienzyme complexes

Baeyer–Villiger Monooxygenases and Their Mechanism of Oxygen Activation: From Microbes to Humans

Structural and Biochemical Studies Enlighten the Unspecific Peroxygenase from Hypoxylon sp. EC38 as an Efficient Oxidative Biocatalyst

Collaborators (5)

Ivana Maric

Arthur Ram

Marco Fraaije

Lígia O. Martins

Eduardo Pinho Melo

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