Andrea Rasola

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Associate Professor

University of Padova

Italy

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About

Andrea Rasola is an Associate Professor at the Università degli Studi di Padova, Italy. Her research focuses on the molecular mechanisms of cancer, particularly the role of hexokinase 2 and mitochondrial chaperones in neoplastic progression. Recent articles highlight her investigations into anti-neoplastic approaches for malignant tumors and the implications of genetic models in understanding POLG-disorders.

Recent Grants

Grant: Close

TRAPping neurofibromas. Inhibition of the mitochondrial chaperone TRAP1 as an anti-neoplastic strategy for NF1-associated tumors

Open Date: 2020-12-01

Close Date: 2021-11-30

Grant: Close

Targeting the mitochondrial chaperone TRAP1 to inhibit plexiform neurofibroma growth

Open Date: 2016-07-18

Close Date: 2017-07-18

Articles (12)

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2024

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2024

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2021

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2021

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2021

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2021

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2021

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2020

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2020

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2020

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2020

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2020

Collaborators (19)

Raquel Brañas Casas

University of Padua

ITALY

Andrea Rasola

Research Interests

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About

Recent Grants

Articles (12)

The Use of Hexokinase 2-Displacing Peptides as an Anti-Neoplastic Approach for Malignant Peripheral Nerve Sheath Tumors

Zebrafish polg2 knock-out recapitulates human POLG-disorders; implications for drug treatment

Neurofibromin Deficiency and Extracellular Matrix Cooperate to Increase Transforming Potential through FAK-Dependent Signaling

Contribution of the CK2 Catalytic Isoforms α and α’ to the Glycolytic Phenotype of Tumor Cells

The molecular chaperone TRAP1 in cancer: From the basics of biology to pharmacological targeting

Defining the molecular mechanisms of the mitochondrial permeability transition through genetic manipulation of F-ATP synthase

Hexokinase 2 in Cancer: A Prima Donna Playing Multiple Characters

Progressively De-Differentiated Pancreatic Cancer Cells Shift from Glycolysis to Oxidative Metabolism and Gain a Quiescent Stem State.

Dynamically Shaping Chaperones. Allosteric Modulators of HSP90 Family as Regulatory Tools of Cell Metabolism in Neoplastic Progression

Hexokinase 2 displacement from mitochondria‐associated membranes prompts Ca 2+ ‐dependent death of cancer cells

Honokiol Bis-Dichloroacetate Is a Selective Allosteric Inhibitor of the Mitochondrial Chaperone TRAP1

S-nitrosylation affects TRAP1 structure and ATPase activity and modulates cell response to apoptotic stimuli

Collaborators (19)

Raquel Brañas Casas

Andrea Battistoni

Carlos Sanchez Martin

federica chiara

Enrico Baruffini

Andrea Vettori

Elisa Dalla Pozza

Giovanni Risato

Lorenzo A. Pinna

Claudia Di Carlo

Chiara Cavallini

Andrea Trevisan

Maria Ruzzene

Luisa Dalla Valle

Stefano Ferraresi

Carlo Viscomi

Maria SCUPOLI

Mauro Salvi

Sara RINALDUCCI

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