Andreas Krause

Chief Scientific Officer

Simulations Plus (United States)

United States

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About

Andreas Krause is the Chief Scientific Officer at Simulations Plus in the United States. His research focuses on pharmacokinetics and pharmacodynamics, with recent articles exploring population pharmacokinetics and concentration-QT analysis. His work includes modeling of novel receptor antagonists and the application of advanced modeling techniques in pharmacometrics.

Articles (8)

Year:

2025

Year:

2025

Year:

2024

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2023

Year:

2023

Year:

2023

Year:

2021

Year:

2020

Collaborators (1)

Clemens Muehlan

Idorsia Pharmaceuticals Ltd

SWITZERLAND

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Andreas Krause

Research Interests

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Articles (8)

The Basel Modeling and Simulation Seminar: 20 Editions of Fostering Local Exchange in Pharmacometrics

Beyond the linear model in concentration-QT analysis

Population pharmacokinetics of the dual endothelin receptor antagonist aprocitentan in subjects with or without essential or resistant hypertension

Population pharmacokinetic modeling of daridorexant, a novel dual orexin receptor antagonist

Mind the Gap: Model-Based Switching from Selatogrel to Maintenance Therapy with Oral P2Y12 Receptor Antagonists

Modeling time‐delayed concentration‐QT effects with ACT‐1014‐6470, a novel oral complement factor 5a receptor 1 (C5a1 receptor) antagonist

PK/PD modeling of a clazosentan thorough QT study with hysteresis in concentration-QT and RR-QT

Modelling pharmacokinetics and pharmacodynamics of the selective S1P1 receptor modulator cenerimod in healthy subjects and systemic lupus erythematosus patients

Collaborators (1)

Clemens Muehlan

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