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Andrei Chabes

Professor

Umea University

Sweden

Research Interests

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Professors in Sweden Professors in Cell Biology Cell Biology professors in Sweden

About

Andrei Chabes is a Professor at Umeå University in Sweden. His research primarily focuses on DNA replication, nucleotide pools, and the mechanisms of replication stress. Recent articles include investigations into dATP and dGTP depletion, the role of ribonucleotide salvage in mitochondrial transcription, and the implications of various DNA polymerases in replication fidelity. Professor Chabes actively contributes to the understanding of epigenetic and metabolic pathways in relation to DNA replication.

Articles (16)

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2026

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2025

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2025

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2025

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2020

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2020

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2020

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2020

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2020

Collaborators (11)

Kiminori Kurashima

特任助教/Research Assistant Professor

基礎生物学研究所/National Institute for Basic Biology

JAPAN

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Magdalena Skrzypczak

Institute of Hematology and Transfusion Medicine

POLAND

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Carlos Gallego-Garcia

Associate Professor

Universidad Francisco de Vitoria

SPAIN

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Karolina Makiela-Dzbenska

Institute of Biochemistry and Biophysics, Polish Academy of Sciences

POLAND

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Haico Van Attikum

Professor/Principal Investigator

Leiden University Medical Center

NETHERLANDS

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Paulina Wanrooij

Umea University

SWEDEN

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Amandine Batté

University of Lausanne

SWITZERLAND

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Iwona J Fijalkowska

professor

Institute of Biochemistry and Biophysics, Polish Academy of Sciences

POLAND

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Lothar Schermelleh

Professor of Bioimaging

University of Oxford

UNITED KINGDOM

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Erik Johansson

Umea University

SWEDEN

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Tomomi Tsubouchi

Graduate University for Advanced Studies

JAPAN

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Andrei Chabes

Research Interests

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Articles (16)

Slow RNAPII elongation enhances naive-pluripotency rewiring while maintaining high replication fork speed

RRM2B deficiency causes dATP and dGTP depletion through enhanced degradation and slower synthesis

Replication-IDentifier links epigenetic and metabolic pathways to the replication stress response

Decoding nucleoside supplementation: how thymidine outperforms ribonucleosides in accelerating mammalian replication forks

NME6: ribonucleotide salvage sustains mitochondrial transcription

Impairment of the non-catalytic subunit Dpb2 of DNA Pol ɛ results in increased involvement of Pol δ on the leading strand.

Quantitative Analysis of Nucleoside Triphosphate Pools in Mouse Muscle Using Hydrophilic Interaction Liquid Chromatography Coupled with Tandem Mass Spectrometry Detection.

Chl1 helicase controls replication fork progression by regulating dNTP pools

Increased contribution of DNA polymerase delta to the leading strand replication in yeast with an impaired CMG helicase complex

dNTP concentrations do not increase in mammalian cells in response to DNA damage.

Isocratic HPLC analysis for the simultaneous determination of dNTPs, rNTPs and ADP in biological samples.

Mec1 Is Activated at the Onset of Normal S Phase by Low-dNTP Pools Impeding DNA Replication

Proofreading deficiency in mitochondrial DNA polymerase does not affect total dNTP pools in mouse embryos

High density of unrepaired genomic ribonucleotides leads to Topoisomerase 1-mediated severe growth defects in absence of ribonucleotide reductase

Inactivation of folylpolyglutamate synthetase Met7 results in genome instability driven by an increased dUTP/dTTP ratio

SAMHD1 Limits the Efficacy of Forodesine in Leukemia by Protecting Cells against the Cytotoxicity of dGTP

Collaborators (11)

Kiminori Kurashima

Magdalena Skrzypczak

Carlos Gallego-Garcia

Karolina Makiela-Dzbenska

Haico Van Attikum

Paulina Wanrooij

Amandine Batté

Iwona J Fijalkowska

Lothar Schermelleh

Erik Johansson

Tomomi Tsubouchi

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