Andrew Stoddart

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University of Edinburgh
Country flagUnited Kingdom

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Recent Grants

Grant: Open

Glucocorticoids in Adults With Acute Respiratory Distress Syndrome: Randomised Clinical Trial (GuARDS Trial)

Open Date: 2023-03-01

Close Date: 2028-02-29

Grant: Close

Designing a platform trial to assess the effectiveness of interventions for peripheral arterial disease: The PAEDIS trial development project.

Open Date: 2023-03-01

Close Date: 2024-02-29

Grant: Close

Venous leg ulcErs: management and eradication, the VEIN Platform Study

Open Date: 2023-03-01

Close Date: 2024-02-29

Grant: Open

What is the clinical-effectiveness and cost-effectiveness of surgery with medial opening wedge high tibial osteotomy (HTO) compared with non-surgical treatment in the management of osteoarthritis (OA) of the knee in patients younger than 60 years? (MOTION Trial)

Open Date: 2022-02-01

Close Date: 2027-01-31

Grant: Close

The impact of REstrictive versUs Liberal Transfusion strategy on cardiac Injury in patients undergoing surgery for Hip Fracture (RESULT-HIP).

Open Date: 2021-08-01

Close Date: 2025-07-31

Articles (8)

Year:

2023

Background Sedentary behaviour is linked to increased risk of type 2 diabetes, cardiovascular disease, musculoskeletal issues and poor mental well-being. Contact (call) centres are associated with higher levels of sedentary behaviour than other office-based workplaces. Stand Up for Health is an adaptive intervention designed to reduce sedentary behaviour in contact centres. Objectives The objectives were to test the acceptability and feasibility of implementing the intervention; to assess the feasibility of the study design and methods; to scope the feasibility of a future health economic evaluation; and to consider the impact of COVID-19 on the intervention. All sites received no intervention for between 3 and 12 months after the start of the study, as a waiting list control. Design This was a cluster-randomised stepped-wedge feasibility design. Setting The trial was set in 11 contact centres across the UK. Participants Eleven contact centres and staff. Intervention Stand Up for Health involved two workshops with staff in which staff developed activities for their context and culture. Activities ranged from using standing desks to individual goal-setting, group walks and changes to workplace policies and procedures. Main outcome measures The primary outcome was accelerometer-measured sedentary time. The secondary outcomes were subjectively measured sedentary time, overall sedentary behaviour, physical activity, productivity, mental well-being and musculoskeletal health. Results Stand Up for Health was implemented in 7 out of 11 centres and was acceptable, feasible and sustainable (objective 1). The COVID-19 pandemic affected the delivery of the intervention, involvement of contact centres, data collection and analysis. Organisational factors were deemed most important to the success of Stand Up for Health but also the most challenging to change. There were also difficulties with the stepped-wedge design, specifically maintaining contact centre interest (objective 2). Feasible methods for estimating cost-efficiency from an NHS and a Personal Social Services perspective were identified, assuming that alternative feasible effectiveness methodology can be applied. Detailed activity-based costing of direct intervention costs was achieved and, therefore, deemed feasible (objective 3). There was significantly more sedentary time spent in the workplace by the centres that received the intervention than those that did not (mean difference 84.06 minutes, 95% confidence interval 4.07 to 164.1 minutes). The other objective outcomes also tended to favour the control group. Limitations There were significant issues with the stepped-wedge design, including difficulties in maintaining centre interest and scheduling data collectio

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2022

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2021

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2020

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2020

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2020

Collaborators (5)

Scott Gordon Cunningham

Academic, Senior Lecturer (Teaching and Research)

University of Dundee

UNITED KINGDOM
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Aisha Holloway

Professor of Nursing Studies

University of Edinburgh

UNITED KINGDOM
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rosie stenhouse

Head of Nursing Studies

University of Edinburgh

UNITED KINGDOM
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Bruce Mason

University of Edinburgh

UNITED KINGDOM
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Jennifer Ferguson

Teesside University

UNITED KINGDOM
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