Andrzej Dziembowski

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International Institute of Molecular and Cell Biology

Poland

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Prof. Andrzej Dziembowski is a faculty member at the International Institute of Molecular and Cell Biology in Poland. His research areas encompass molecular biology and RNA biology, with recent publications focusing on mRNA profiling, deadenylation, and the physiological roles of genes in C. elegans. He is engaged in developing methods for RNA analysis and investigating complex interactions in gene expression and regulation.

Recent Grants

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Rola cytoplazmatycznej poliadenylacji w regulacji lokalnej translacji w neuronach

Open Date: 2020-09-01

Close Date: 2023-09-01

Grant: Close

Mechanizmy onkogenezy związanej z mutacjami w DIS3

Open Date: 2017-05-19

Close Date: 2022-05-18

Grant: Close

Posttranscriptional regulation of gene expression in metazoans.

Open Date: 2015-01-01

Close Date: 2017-12-31

Grant: Close

Analiza wpływu mutacji w DIS3 na przeżywalność, rozwój embrionalny i powstawanie nowotworów u myszy.

Open Date: 2014-05-19

Close Date: 2017-05-18

Grant: Close

Regulation of Gene Expression by non-canonical poly(A) and poly(U) polymerases

Open Date: 2013-02-01

Close Date: 2018-01-31

Articles (16)

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2025

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2021

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2021

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2021

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2021

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2021

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2020

Collaborators (19)

Dominika Nowis

head

Medical University of Warsaw

POLAND

Andrzej Dziembowski

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Recent Grants

Articles (16)

Direct profiling of non-adenosines in poly(A) tails of endogenous and therapeutic mRNAs with Ninetails

5' terminal nucleotide determines the immunogenicity of IVT RNAs.

Excretory gland cell and NSPC genes in C. elegans: investigating their physiological roles

Comprehensive analysis of poly(A) tails in mouse testes and ovaries using Nanopore Direct RNA Sequencing

Structure-functional characterization of Lactococcus AbiA phage defense system

Modeling of mRNA deadenylation rates reveal a complex relationship between mRNA deadenylation and decay

Measuring the tail: Methods for poly(A) tail profiling

A long noncoding RNA promotes parasite differentiation in African trypanosomes

Reproducible and efficient new method of RNA 3’-end labelling by CutA nucleotidyltransferase-mediated CC-tailing

Three-layered control of mRNA poly(A) tail synthesis in Saccharomyces cerevisiae

Landscape of functional interactions of human processive ribonucleases revealed by high-throughput siRNA screenings

Global view on the metabolism of RNA poly(A) tails in yeast Saccharomyces cerevisiae

Functions and mechanisms of RNA tailing by metazoan terminal nucleotidyltransferases

Cytoplasmic polyadenylation by TENT5A is required for proper bone formation

The TUTase URT1 connects decapping activators and prevents the accumulation of excessively deadenylated mRNAs to avoid siRNA biogenesis

Immunoglobulin expression and the humoral immune response is regulated by the non-canonical poly(A) polymerase TENT5C

Collaborators (19)

Dominika Nowis

Małgorzata Figiel

Ewa Borsuk

Juri Rappsilber

Katarzyna Matylla-Kulińska

Gracjan Michlewski

Krzysztof Skowronek

Dominique Gagliardi

Marcus Johansson

Karolina Drazkowska

Roman Szczesny

Malwina Hyjek-Składanowska

Zuzanna Mackiewicz

Monika Kusio-Kobialka

Rafal Tomecki

Seweryn Mroczek

Kamil Kobyłecki

Luisa M. Figueiredo

Matti Turtola

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