Andy Wullaert

Associate professor

University of Antwerp

Belgium

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Andy Wullaert is an Associate Professor at the University of Antwerp, Belgium. His research focuses on myeloid cell biology, immune responses in humanized mouse models, and the mechanisms underlying autoinflammatory syndromes. Recent publications include studies on myeloid engraftment in mice and the role of specific proteins in immune modulation and gastrointestinal infections.

Articles (18)

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2025

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2024

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2024

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2023

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2023

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2023

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2023

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2023

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2022

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2022

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2021

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2021

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2020

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2020

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2020

Collaborators (12)

mathieu bertrand

Associate Professor (100% ZAP)

Ghent University

BELGIUM

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Selina Kathleen Jorch

Professor

University of Münster

GERMANY

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Philip Rosenstiel

Kiel University

GERMANY

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Els Lebegge

Vrije Universiteit Brussel

BELGIUM

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Pauline Bardet

Vrije Universiteit Brussel

BELGIUM

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Yvon Elkrim

Vrije Universiteit Brussel

BELGIUM

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Mohamed Lamkanfi

BELGIUM

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Markus Sperandio

Prof. Dr. med.

Ludwig-Maximilians-Universität München

GERMANY

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Elisabeth Nyström

University of Gothenburg

SWEDEN

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SANA ARNOUK

Vrije Universiteit Brussel

BELGIUM

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Jan Brughmans

Vrije Universiteit Brussel

BELGIUM

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Helena Van Damme

Vrije Universiteit Brussel

BELGIUM

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Andy Wullaert

Research Interests

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Articles (18)

Neonatal microbiota colonization primes maturation of goblet cell–mediated protection in the pre-weaning colon

Advances in human myeloid-engrafting NSG-SGM3 and MISTRG mice

Development of human innate immune responses in a humanized mouse model expressing four human myelopoiesis transgenes.

Caspase-12 is Expressed in Purkinje Neurons and Prevents Psychiatric-Like Behavior in Mice.

Myeloid A20 is critical for alternative macrophage polarization and type-2 immune-mediated helminth resistance.

Complex regulation of alarmins S100A8/A9 and secretion via Gasdermin-D pores exacerbates autoinflammation in Familial Mediterranean Fever.

Gasdermin D independent canonical inflammasome responses cooperate with caspase-8 to establish host defense against gastrointestinal Citrobacter rodentium infection

Recent Insights in Pyrin Inflammasome Activation: Identifying Potential Novel Therapeutic Approaches in Pyrin-Associated Autoinflammatory Syndromes.

The autoinflammation-associated NLRC4<sup>V341A</sup> mutation increases microbiota-independent IL-18 production but does not recapitulate human autoinflammatory symptoms in mice.

Myeloid OTULIN deficiency couples RIPK3-dependent cell death to Nlrp3 inflammasome activation and IL-1β secretion

Protein citrullination and NET formation do not contribute to the pathology of A20/TNFAIP3 mutant mice.

<scp>GSDMD</scp> drives canonical inflammasome‐induced neutrophil pyroptosis and is dispensable for <scp>NETosis</scp>

Nlrp3 inflammasome activation in macrophages suffices for inducing autoinflammation in mice

IL1β Promotes Immune Suppression in the Tumor Microenvironment Independent of the Inflammasome and Gasdermin D

Punching Holes in Cellular Membranes: Biology and Evolution of Gasdermins.

Two distinct ubiquitin-binding motifs in A20 mediate its anti-inflammatory and cell-protective activities

Excessive phospholipid peroxidation distinguishes ferroptosis from other cell death modes including pyroptosis

Zeb2 drives invasive and microbiota-dependent colon carcinoma

Collaborators (12)

mathieu bertrand

Selina Kathleen Jorch

Philip Rosenstiel

Els Lebegge

Pauline Bardet

Yvon Elkrim

Mohamed Lamkanfi

Markus Sperandio

Elisabeth Nyström

SANA ARNOUK

Jan Brughmans

Helena Van Damme

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