Angela Greenman

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University of Arizona College of Medicine
Country flagUnited States

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The role of cardiac myosin binding protein-C central domains in regulating cardiac contraction

Open Date: 2022-04-01

Close Date: 2024-03-30

Articles (6)

Year:

2023

Year:

2023

We examined the effects of training on the myofilament calcium in diabetic rat hearts. After 8 wk of treadmill running, both nondiabetic and diabetic cardiomyocytes had increased myofilament calcium sensitivity compared with their sedentary counterparts, but there was no effect of training on the phosphorylation or O-GlcNAcylation status of myofilament proteins measured in this study. These data highlight one potential mechanism capable of reversing, in part, reduced cardiac reserve in the diabetic heart.

Year:

2022

Year:

2022

Year:

2021

Year:

2020

Collaborators (2)

James C. Baldi

University of Otago

NEW ZEALAND
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Joyce Koh

Associate Professor

University of Otago

NEW ZEALAND
View details
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