Angela Greenman
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The role of cardiac myosin binding protein-C central domains in regulating cardiac contraction
Open Date: 2022-04-01
Close Date: 2024-03-30
Articles (6)
Year:
2023
Year:
2023
We examined the effects of training on the myofilament calcium in diabetic rat hearts. After 8 wk of treadmill running, both nondiabetic and diabetic cardiomyocytes had increased myofilament calcium sensitivity compared with their sedentary counterparts, but there was no effect of training on the phosphorylation or O-GlcNAcylation status of myofilament proteins measured in this study. These data highlight one potential mechanism capable of reversing, in part, reduced cardiac reserve in the diabetic heart.
Year:
2022
Year:
2022
Year:
2021
Year:
2020
Collaborators (2)
James C. Baldi
University of Otago
Joyce Koh
Associate Professor
University of Otago
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