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Angelika Riemer

Has grant

Division Head

Deutsches Krebsforschungszentrum

Germany

Research Interests

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Recent Grants

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Identification and validation of mutation-derived tumor neoepitopes for immunotherapy approaches

Open Date: 2017-09-01

Close Date: 2020-12-01

Grant: Close

Molecular Vaccine Design

Open Date: 2015-02-01

Close Date: 2020-12-01

Grant: Close

Funding for large instrumentation

Open Date: 2013-01-01

Close Date: 2017-01-01

Grant: Close

Antibodies suitable for HLA type-specific immunoprecipitation

Open Date: 2012-01-01

Close Date: 2013-01-01

Grant: Close

THERAVAC - Development of a therapeutic HPV vaccine via target epitope identification by mass spectrometry

Open Date: 2011-01-01

Close Date: 2014-01-01

Articles (17)

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Collaborators (9)

Peter van Veelen

Leiden University Medical Center

NETHERLANDS

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Marten Meyer

Deputy Head

German Cancer Research Center

GERMANY

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Stefan Eichmüller

Head

German Cancer Research Center (DKFZ)

GERMANY

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Philipp Uhl

GERMANY

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Marco Antonio Mendoza-Parra

Research Director (DR2) CNRS

Centre National de la Recherche Scientifique (CNRS)

FRANCE

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Michael Volkmar

Head

GERMANY

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Carine Michiels

Full Professor

University of Namur

BELGIUM

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Michael Platten

Heidelberg University

GERMANY

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Michael Schmitt

Full Professor

UniversitätsKlinikum Heidelberg

GERMANY

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Angelika Riemer

Research Interests

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Recent Grants

Articles (17)

Dissection of the T-cell infiltrate in mouse pancreatic tumors reveals an extensive and diverse tumor-reactive T-cell repertoire

Systematic Workflow Optimization for Ultra-sensitive Targeted Immunopeptidomics

A targetable dependency on nonsense-mediated decay for cellular homeostasis and immune control in small cell lung cancer

Multiomic profiling links L1 retrotransposition to genomic instability and ecDNA in bladder cancer

The current landscape of therapeutic vaccination approaches for treatment of HPV-dependent malignancies

Vaccine-induced T cell receptor T cell therapy targeting a glioblastoma stemness antigen

A versatile silica nanoparticle platform for induction of T cell responses – applied for therapeutic vaccination against HPV16 E6/E7-positive tumors in MHC-humanized mice

Upstream open reading frame translation enhances immunogenic peptide presentation in mitotically arrested cancer cells

Enhanced mutanome analysis towards the induction of neoepitope-reactive T-cell responses for personalized immunotherapy of pancreatic cancer.

Highly sensitive live-cell imaging-based cytotoxicity assay enables functional validation of rare epitope-specific CTLs.

optiPRM: A Targeted Immunopeptidomics LC-MS Workflow With Ultra-High Sensitivity for the Detection of Mutation-Derived Tumor Neoepitopes From Limited Input Material

MediMer: a versatile do-it-yourself peptide-receptive MHC class I multimer platform for tumor neoantigen-specific T cell detection.

Meeting report: Considerations for trial design and endpoints in licensing therapeutic HPV16/18 vaccines to prevent cervical cancer.

Development of an Orthotopic HPV16-Dependent Base of Tongue Tumor Model in MHC-Humanized Mice

Definition and Characterization of SOX11-Derived T Cell Epitopes towards Immunotherapy of Glioma

Transcriptome-based identification of tumor-reactive and bystander CD8<sup>+</sup> T cell receptor clonotypes in human pancreatic cancer.

Characterization of DoTc2 4510—Identifying HPV16 Presence in a Cervical Carcinoma Cell Line Previously Considered to Be HPV-Negative

Collaborators (9)

Peter van Veelen

Marten Meyer

Stefan Eichmüller

Philipp Uhl

Marco Antonio Mendoza-Parra

Michael Volkmar

Carine Michiels

Michael Platten

Michael Schmitt

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