Angelo D'Alessandro

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Full Professor

University of Colorado Anschutz Medical Campus

United States

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Angelo D'Alessandro is a Full Professor at the University of Colorado Anschutz Medical Campus in the United States. His research focuses on metabolic adaptations in hematopoiesis, inflammatory resolution, and the biochemical pathways involved in various hematological conditions. His recent publications include studies on tissue transglutaminase in trauma patients, erythropoiesis linked to inflammation, and metabolic reprogramming in erythroblasts.

Recent Grants

Grant: Close

Interactions between the ADORA2b/Sphk1axis and the AE1-Hb switch in red blood cell aging in vivo and in vitro

Open Date: 2020-03-15

Close Date: 2024-02-29

Grant: Close

MIRAGES: Metabolic Investigation of Red blood cells as a function of Aging, Genetics, Environment, and Storage

Open Date: 2020-03-05

Close Date: 2022-02-28

Grant: Close

The Impact of Oxidative Stress on Erythocyte Biology

Open Date: 2019-09-25

Close Date: 2023-08-31

Grant: Close

PIMT1 in Red Blood Cell aging in vivo and in vitro

Open Date: 2019-08-01

Close Date: 2024-04-30

Grant: Close

Resuscitation Strategies for Achieving Thrombo-inflammatory Homeostasis

Open Date: 2019-05-20

Close Date: 2024-04-30

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Collaborators (13)

David Irwin

Associate Professor

University of Colorado School of Medicine

UNITED STATES

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Sarah Skinner

University Hospital of Montpellier

FRANCE

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Vassilis Tzounakas

Assistant Professor

University of Patras

GREECE

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Ariel Hay

University of Virginia

UNITED STATES

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Travis Nemkov

UNITED STATES

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Steven Spitalnik

Professor

Columbia University

UNITED STATES

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Andrew Subudhi

Professor and Chair

University of Colorado Colorado Springs

UNITED STATES

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ANDREA MATTAREI

Associate Professor

Università degli Studi della Campania Luigi Vanvitelli Scuola di Medicina e Chirurgia

ITALY

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Kirk C. Hansen

University of Colorado Boulder

UNITED STATES

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Susan Wolf

Regents Professor; McKnight Presidential Professor of Law, Medicine & Public Policy; Faegre Drinker Professor of Law; Professor of Medicine

University of Minnesota

UNITED STATES

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Shannon Tessier

Assistant Professor

Massachusetts General Hospital

UNITED STATES

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Anastasios Kriebardis

Associate Professor

University of West Attica

GREECE

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Seyed Mehdi Nouraie

Associate Professor

University of Pittsburgh

UNITED STATES

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Angelo D'Alessandro

Research Interests

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About

Recent Grants

Articles (20)

Increased Exercise Tolerance in G6PD African Variant Mice Driven by Metabolic Adaptations and Erythrophagocytosis

Tissue transglutaminase drives fibrin β-chain cross-linking: a novel fibrin modification observed in trauma patients

Resolution of inflammation increases erythropoiesis

Metabolic Adaptation of Regenerative Hematopoiesis Depends on Docking-Independent Mitochondrial Connexin-43

Multiomics reveal plasma constituents associated with thrombosis among trauma patients who do not respond to enoxaparin

Mitapivat metabolically reprograms human β-thalassemic erythroblasts, increasing their responsiveness to oxidation

Advancing the Biochemical Understanding of Maple Syrup Urine Disease and the Impact of Liver Transplantation: A Pilot Study

Glycolytic disruption restricts Drosophila melanogaster larval growth via the cytokine Upd3

Red Blood Cell Metabolic Responses during Acute Hypoxic Exercise in Healthy Adults

RBC-GEM: A genome-scale metabolic model for systems biology of the human red blood cell

PFKFB3 Inhibits Fructose Metabolism in Pulmonary Microvascular Endothelial Cells

Red Blood Cells from Individuals with Lesch–Nyhan Syndrome: Multi-Omics Insights into a Novel S162N Mutation Causing Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency

Longitudinal metabolic study of red blood cells from patients undergoing gender-affirming testosterone therapy

Assessment of stored red blood cells through lab-on-a-chip technologies for precision transfusion medicine

Metabolic Signatures of Performance in Elite World Tour Professional Male Cyclists

Omics markers of platelet transfusion in trauma patients

Red Blood Cell Storage: From Genome to Exposome Towards Personalized Transfusion Medicine

Metabolic Profile of Individuals with and without Type 2 Diabetes from Sub-Saharan Africa

In vivo evaluation of the effect of sickle cell hemoglobin S, C and therapeutic transfusion on erythrocyte metabolism and cardiorenal dysfunction

Red Blood Cell Metabolism In Vivo and In Vitro

Collaborators (13)

David Irwin

Sarah Skinner

Vassilis Tzounakas

Ariel Hay

Travis Nemkov

Steven Spitalnik

Andrew Subudhi

ANDREA MATTAREI

Kirk C. Hansen

Susan Wolf

Shannon Tessier

Anastasios Kriebardis

Seyed Mehdi Nouraie

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