Anil Jegga

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Professor

Cincinnati Children's Hospital Medical Center

United States

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About

Professor Anil Jegga is a faculty member at Cincinnati Children's Hospital Medical Center in the United States. His research focuses on drug discovery, gene networks, and the molecular mechanisms underlying fibrotic lung diseases and cancers. Recent articles include studies on gene co-expression networks, therapeutic approaches for various conditions, and the role of specific metabolites in disease pathology.

Recent Grants

Grant: Close

Preclinical characterization of saracatinib for cystic fibrosis therapy

Open Date: 2018-09-15

Close Date: 2021-08-31

Grant: Close

Discovery and characterization of candidate therapeutics for drug-induced pulmonary disease

Open Date: 2017-01-01

Close Date: 2018-12-31

Grant: Close

Integrative analysis of multi-omics data to target fibroblast activation in IPF

Open Date: 2016-07-05

Close Date: 2018-06-30

Articles (16)

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2025

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2024

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2023

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2023

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2022

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2022

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2022

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2022

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2021

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2021

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2021

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2021

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2020

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2020

Collaborators (5)

Jing Chen

Assistant Professor

Cincinnati Children's Hospital Medical Center

UNITED STATES

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Debora Sinner

Assistant Professor

UNITED STATES

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Wei Huang

Assistant Professor

University of Cincinnati College of Medicine

UNITED STATES

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Wenbin Tan

University of South Carolina

UNITED STATES

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Yunguan Wang

Assistant Professor

Cincinnati Children's Hospital Medical Center

UNITED STATES

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Anil Jegga

Research Interests

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About

Recent Grants

Articles (16)

From Gene Networks to Therapeutics: A Causal Inference and Deep Learning Approach for Drug Discovery

Wilms tumor 1 impairs apoptotic clearance of fibroblasts in distal fibrotic lung lesions

SEMA3B inhibits TGFβ-induced extracellular matrix protein production and its reduced levels are associated with a decline in lung function in IPF

Perturbations of Glutathione and Sphingosine Metabolites in Port Wine Birthmark Patient-Derived Induced Pluripotent Stem Cells

BRD9-SMAD2/3 orchestrates stemness and tumorigenesis in pancreatic ductal adenocarcinoma

MGATRx: Discovering Drug Repositioning Candidates Using Multi-View Graph Attention

Consensus Gene Co-Expression Network Analysis Identifies Novel Genes Associated with Severity of Fibrotic Lung Disease

GraMDTA: Multimodal Graph Neural Networks for Predicting Drug-Target Associations

Consensus Gene Co-Expression Network Analysis Identifies Novel Genes Associated with Severity of Fibrotic Lung Disease

Eicosatetraynoic Acid and Butyrate Regulate Human Intestinal Organoid Mitochondrial and Extracellular Matrix Pathways Implicated in Crohn's Disease Strictures

Sectm1a deficiency aggravates inflammation-triggered cardiac dysfunction through disruption of LXRα signalling in macrophages.

Computational workflow for functional characterization of COVID-19 through secondary data analysis

Dysregulated overexpression of Sox9 induces fibroblast activation in pulmonary fibrosis

Secondary analysis of transcriptomes of SARS-CoV-2 infection models to characterize COVID-19

Inhibition of Aurora Kinase B attenuates fibroblast activation and pulmonary fibrosis

Pan-transcriptome-based candidate therapeutic discovery for idiopathic pulmonary fibrosis

Collaborators (5)

Jing Chen

Debora Sinner

Wei Huang

Wenbin Tan

Yunguan Wang

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