Ann Hessell

Research Professor

Oregon Health & Science University

United States

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Ann Hessell is a Research Professor at Oregon Health & Science University (OHSU) in the United States. Her research focuses on HIV-1 immunology, including the molecular determinants of HIV resistance, the role of non-neutralizing antibodies, and vaccine-induced immune responses. She has contributed significantly to studies on HIV antibody function and vaccine efficacy, particularly in non-human primate models.

Articles (11)

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2023

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2022

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2022

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2021

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2021

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2021

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2021

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2021

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2020

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2020

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2020

Collaborators (2)

Nancy Haigwood

Director and Professor

UNITED STATES

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Javier Rangel-Moreno

Research Associate Professor

University of Rochester

UNITED STATES

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Ann Hessell

Research Interests

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Articles (11)

Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir

Phagocytosis by an HIV antibody is associated with reduced viremia irrespective of enhanced complement lysis

Non-neutralizing antibodies targeting the immunogenic regions of HIV-1 envelope reduce mucosal infection and virus burden in humanized mice.

CD4+ T Cells Are Dispensable for Induction of Broad Heterologous HIV Neutralizing Antibodies in Rhesus Macaques.

A large repertoire of B cell lineages targeting one cluster of epitopes in a vaccinated rhesus macaque

Polyfunctional tier 2-neutralizing antibodies cloned following hiv-1 env macaque immunization mirror native antibodies in a human donor

Revisiting an IgG Fc Loss-of-Function Experiment: the Role of Complement in HIV Broadly Neutralizing Antibody b12 Activity.

Virus Control in Vaccinated Rhesus Macaques Is Associated with Neutralizing and Capturing Antibodies against the SHIV Challenge Virus but Not with V1V2 Vaccine–Induced Anti-V2 Antibodies Alone

Efficacy of silk fibroin biomaterial vehicle for in vivo mucosal delivery of Griffithsin and protection against HIV and SHIV infection ex vivo.

An HIV Vaccine Targeting the V2 Region of the HIV Envelope Induces a Highly Durable Polyfunctional Fc-Mediated Antibody Response in Rhesus Macaques.

Rapid Induction of Multifunctional Antibodies in Rabbits and Macaques by Clade C HIV-1 CAP257 Envelopes Circulating During Epitope-Specific Neutralization Breadth Development.

Collaborators (2)

Nancy Haigwood

Javier Rangel-Moreno

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