Anne Barton

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Professor of Rheumatology

The University of Manchester

United Kingdom

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About

Anne Barton is a Professor of Rheumatology at the University of Manchester, UK. Her research focuses on the diagnosis and treatment of rheumatological diseases, with recent studies examining aspects like misdiagnosis in inflammatory arthritis, the impact of genetic factors on rheumatoid arthritis, and the effectiveness of drug adherence in psoriasis. She is actively involved in advancing targeted therapeutics and improving patient outcomes through innovative research methodologies.

Recent Grants

Grant: Close

Maximising Therapeutic Utility in Rheumatoid Arthritis

Open Date: 2014-03-01

Close Date: 2018-02-01

Grant: Close

Investigating regions of linkage homologous to those linked with animal models of inflammatory arthritis

Open Date: 1998-09-01

Close Date: 2001-08-01

Articles (20)

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2025

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2025

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2025

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2025

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2025

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2025

Psoriasis is a common inflammatory skin condition affecting approximately 2–3% of people worldwide. Methotrexate (MTX) is a cheap and effective drug that is often recommended as the first-choice systemic agent for psoriasis. Around 40–50% of patients achieve a good response; however, mechanisms of nonresponse are poorly understood. It is not known whether biochemical MTX adherence in patients with psoriasis is suboptimal and requires intervention. Our aim was to audit biochemical MTX adherence using a sensitive liquid chromatography–tandem mass spectrometry in patients prescribed oral MTX for the treatment of psoriasis at our tertiary dermatology centre. Ethical approval for this audit was not required as confirmed by the Health Research Authority.

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2024

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2024

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2024

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2023

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2023

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2023

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2023

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2023

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2023

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2023

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2023

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2023

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2023

Year:

2022

Collaborators (22)

Nasimah Maricar

University of Manchester

UNITED KINGDOM

Anne Barton

Research Interests

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About

Recent Grants

Articles (20)

Pretreatment absolute monocyte counts are associated with biological disease-modifying anti-rheumatic drug non-response in patients with rheumatoid arthritis

Pre-treatment GlycA measurement provides no additional predictive utility beyond routine clinical measures in patients with rheumatoid arthritis

Genome‐Wide Aggregated Trans Effects Analysis Identifies Genes Encoding Immune Checkpoints as Core Genes for Rheumatoid Arthritis

Misdiagnosis and prevalence of rheumatological diseases in early inflammatory arthritis clinic: results from a UK single-centre retrospective cohort study

Estimating pain visual analogue scale from health assessment questionnaire for rheumatoid arthritis with beta mixture models

Genetics of psoriasis spectrum disease – Advances in targeted therapeutics meeting

The use of serum methotrexate level as an assessment of biochemical drug adherence in psoriasis

Factors facilitating and hindering South Asian immigrant adults from engaging in exercise and physical activity – a qualitative systematic review

Ultrasound-guided synovial tissue biopsy for people with rheumatoid arthritis: a micro-costing study

Socioeconomic deprivation is associated with reduced response and lower treatment persistence with TNF inhibitors in rheumatoid arthritis

The Effect of COVID-19 on Medication Adherence in a Rheumatoid Arthritis (BRAGGSS) and Psoriatic Arthritis (OUTPASS) UK Cohort

BBmix: a Bayesian beta-binomial mixture model for accurate genotyping from RNA-sequencing

HLA-DRB1 and HLA-DQA1 associated with immunogenicity to adalimumab therapy in patients with rheumatoid arthritis

A proteomics study of rheumatoid arthritis patients on etanercept identifies putative biomarkers associated with clinical outcome measures

Non-trough adalimumab and certolizumab drug levels associated with a therapeutic EULAR response in adherent patients with rheumatoid arthritis

Association between psoriatic disease and lifestyle factors and comorbidities: cross-sectional analysis and Mendelian randomization

Genetically proxied TYK2 inhibition is associated with reduced sarcoidosis susceptibility

Do genetics contribute to TNF inhibitor response prediction in Psoriatic Arthritis?

Non-trough serum drug levels of adalimumab and etanercept are associated with response in patients with psoriatic arthritis

Omics and Multi-Omics Analysis for the Early Identification and Improved Outcome of Patients with Psoriatic Arthritis

Collaborators (22)

Nasimah Maricar

Darren Plant

Stephen R. Pennington

Megan Sutcliffe

Ryan Malcolm Hum

Jamie Sergeant

Pauline Ho

Annika Bendes

John Bowes

James Galloway

Nisha Nair

Meghna Jani

Chris Wallace

Jenny Humphreys

James Bluett

Myles J Lewis

Vassilios Ioannidis

Hector Chinoy

Chuan Fu Yap

Andrew Filer

Katherine Payne

Andrew Morris

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