Anne-Claude Gavin

Professor

University of Geneva

Switzerland

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Anne-Claude Gavin is a Professor at the University of Geneva in Switzerland. Her research focuses on hematopoietic stem cells, cholesterol metabolism, and cellular homeostasis, as evidenced by her recent publications. She has explored topics such as senescence in aged human cells, the role of APOE in cellular functions, and the mechanisms of ceramide release. Professor Gavin's work contributes to the understanding of metabolic processes and their implications for aging and cellular health.

Articles (14)

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2025

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2024

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2024

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2024

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2024

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2023

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2023

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2022

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2022

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2021

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2021

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2020

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2020

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2020

Collaborators (6)

Anthony D. Ho

Chair and Professor

Ruprecht Karls Universität Heidelberg

GERMANY

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Motomu Tanaka

Professor

Kyoto University

JAPAN

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Nathalie Reuter

Professor

University of Bergen

NORWAY

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Steven V. Ley

UNITED KINGDOM

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Christian Tackenberg

University of Zurich

SWITZERLAND

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Reza Talandashti

University of Oxford

UNITED KINGDOM

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Anne-Claude Gavin

Research Interests

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Articles (14)

A Senescent Cluster in Aged Human Hematopoietic Stem Cell Compartment as Target for Senotherapy

A Membrane-Assisted Mechanism for the Release of Ceramide from the CERT START Domain

Membrane specificity of the human cholesterol transfer protein STARD4

Isoform- and cell-state-specific APOE homeostasis and function

Development of Genetically Encoded Fluorescent KSR1-Based Probes to Track Ceramides during Phagocytosis

CLICK-chemoproteomics and molecular dynamics simulation reveals pregnenolone targets and their binding conformations in Th2 cells

Differential intracellular management of fatty acids impacts on metabolic stress-stimulated glucose uptake in cardiomyocytes

Glucose Metabolism and Aging of Hematopoietic Stem and Progenitor Cells

In vitro and in cellulo ApoE particle formation, isolation, and characterization

APOE2, E3, and E4 differentially modulate cellular homeostasis, cholesterol metabolism, and inflammatory response in isogenic iPSC-derived astrocytes.

CLICK-enabled analogues reveal pregnenolone interactomes in cancer and immune cells

Structures of three MORN repeat proteins and a re-evaluation of the proposed lipid-binding properties of MORN repeats.

The Ribomethylome Landscape of Hematopoietic System

Structural insights and activating mutations in diverse pathologies define mechanisms of deregulation for phospholipase C gamma enzymes.

Collaborators (6)

Anthony D. Ho

Motomu Tanaka

Nathalie Reuter

Steven V. Ley

Christian Tackenberg

Reza Talandashti

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