Anne Willis

Director/Professor of Toxicology

United Kingdom

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About

Anne Willis is a Professor and Director of Toxicology at the MRC Toxicology Unit in the UK. Her research focuses on RNA-protein interactions, ribosomal dynamics, and the impact of oxidative stress on cellular metabolism. Recent publications highlight her contributions to understanding the mechanisms of cancer, obesity, and viral detection methods.

Articles (16)

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2024

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2024

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2024

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2022

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2021

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2021

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2021

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2021

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2021

Collaborators (21)

David Gatfield

University of Lausanne

SWITZERLAND

Anne Willis

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Articles (16)

Interrogation of RNA-protein interaction dynamics in bacterial growth

RNA helicase EIF4A1-mediated translation is essential for the GC response

System-wide analysis of RNA and protein subcellular localization dynamics

ROS-induced ribosome impairment underlies ZAKα-mediated metabolic decline in obesity and aging.

Crosstalk with lung fibroblasts shapes the growth and therapeutic response of mesothelioma cells.

N<sup>1</sup>-methylpseudouridylation of mRNA causes +1 ribosomal frameshifting.

Evaluating data integrity in ribosome footprinting datasets through modelled polysome profiles

Eukaryotic Elongation Factor 2 Kinase Activity Is Required for the Phenotypes of the Rpl24 Mouse

Extracellular Vesicles Isolated from Malignant Mesothelioma Cancer-Associated Fibroblasts Induce Pro-Oncogenic Changes in Healthy Mesothelial Cells

Development of a colorimetric assay for the detection of SARS-CoV-2 3CLpro activity

Unresolved stalled ribosome complexes restrict cell-cycle progression after genotoxic stress.

Integrated genomics point to immune vulnerabilities in pleural mesothelioma.

Don't shoot the messenger… shoot the reader.

The pathogenesis of mesothelioma is driven by a dysregulated translatome.

Hypoxia: Uncharged tRNA to the Rescue!

The mTOR regulated RNA-binding protein LARP1 requires PABPC1 for guided mRNA interaction.

Collaborators (21)

David Gatfield

Anders Lund

Leonardo Mancini

C. Mark Smales

Christopher Proud

Melanie Blasius

Béatrice Choi

Tobias von der Haar

Mary Elizabeth Pownall

John Knight

Oliver Crook

Pavel Baranov

Martin Turner

Daniel Murphy

Lajos Kalmár

Owen J. Sansom

Morten Dall

Kathryn Lilley

David Michael Gay

Anna Constance Vind

Benjamin Jensen

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