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Anthony Moorman

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Professor of Genetic Epidemiology

Newcastle University

United Kingdom

Research Interests

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Recent Grants

Grant: Open

• BIOINFORM: Biologically informed treatment decisions in acute leukaemia

Open Date: 2025-05-01

Close Date: 2030-04-01

Grant: Close

ALLTogether for Research (A2G4R) Knowledge Hub

Open Date: 2024-06-01

Close Date: 2026-05-31

Grant: Close

Harnessing Big Data to Drive Precision Medicine in Acute Lymphoblastic Leukaemia

Open Date: 2022-07-01

Close Date: 2025-06-30

Grant: Close

Evaluating integrated and multi-biomarker driven risk stratification in paediatric acute lymphoblastic leukaemia

Open Date: 2022-01-01

Close Date: 2024-12-31

Articles (20)

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Collaborators (14)

John Lunec

UNITED KINGDOM

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Hanne Vibeke Hansen Marquart

Chief Physician; MD, PhD, Clinical Associate Professor

Copenhagen University Hospital

DENMARK

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Andrea Biondi

Full Professor

University of Milano-Bicocca

ITALY

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Hélène Cavé

PUPH, Head of the molecular Genetics unit

Hôpital Robert-Debré

FRANCE

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Juan Esteban Arango Ossa

Sloan Kettering Institute

UNITED STATES

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Joan Boyes

Associate Professor

University of Leeds

UNITED KINGDOM

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Marc Mansour

Professor

University College London

UNITED KINGDOM

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Josep Maria Ribera Santasusana

Chief of the Department

Institut Català d'Oncologia

SPAIN

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Vaskar Saha

The University of Manchester

UNITED KINGDOM

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Tiina Vesterinen

University of Helsinki

FINLAND

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Doris Steinemann

Prof. Dr. rer. nat

Medizinische Hochschule Hannover

GERMANY

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Amir Enshaei

Newcastle University

UNITED KINGDOM

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David Westhead

Prof

University of Leeds

UNITED KINGDOM

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Pamela Kearns

University of Birmingham

UNITED KINGDOM

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Anthony Moorman

Research Interests

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Recent Grants

Articles (20)

EARLY RESPONSE AND GENETICS DEFINE RELAPSE RISK AFTER FRONTLINE BLINATUMOMAB IN CHILDHOOD B-ALL: A COHORT STUDY

ALLTogether recommendations for biobanking samples from patients with acute lymphoblastic leukaemia

Excised DNA circles from V(D)J recombination promote relapsed leukaemia

PAX5::AUTS2 childhood B-ALL: a relapse-prone genetic subtype with frequent central nervous system involvement and a poor outcome

DUX4-rearranged B-ALL: deciphering a biological and clinical conundrum

A dedicated caller for DUX4 rearrangements from whole-genome sequencing data

A robust and validated integrated prognostic index for defining risk groups in adult acute lymphoblastic leukemia: an EWALL collaborative study

ETV6::RUNX1 Acute Lymphoblastic Leukemia: how much therapy is needed for cure?

Combination p53 activation and BCL-xL/BCL-2 inhibition as a therapeutic strategy in high-risk and relapsed acute lymphoblastic leukemia

Integration of genetics and MRD to define low risk patients with B-cell precursor acute lymphoblastic leukaemia with intermediate MRD levels at the end of induction

Noncoding mutations drive persistence of a founder preleukemic clone which initiates late relapse in T-ALL.

Results from UKALL60+, a phase 2 study in older patients with untreated acute lymphoblastic leukemia

Targeted treatment options for paediatric B-cell precursor acute lymphoblastic leukaemia patients with constitutional or somatic chromosome 21 alterations

Cranial radiotherapy has minimal benefit in children with central nervous system involvement in T-ALL.

Blinatumomab for First-Line Treatment of Children and Young Persons With B-ALL.

Disruption to the FOXO-PRDM1 axis resulting from deletions of chromosome 6 in acute lymphoblastic leukaemia.

Diagnostic utility of whole genome sequencing in adults with B-other acute lymphoblastic leukemia

Dasatinib with intensive chemotherapy in de novo paediatric Philadelphia chromosome-positive acute lymphoblastic leukaemia (CA180-372/COG AALL1122): a single-arm, multicentre, phase 2 trial.

Clinical characteristics and outcomes of B-cell precursor ALL with MEF2D rearrangements: a retrospective study by the Ponte di Legno Childhood ALL Working Group

Detection of constitutional mismatch repair deficiency in children and adolescents with acute lymphoblastic leukemia

Collaborators (14)

John Lunec

Hanne Vibeke Hansen Marquart

Andrea Biondi

Hélène Cavé

Juan Esteban Arango Ossa

Joan Boyes

Marc Mansour

Josep Maria Ribera Santasusana

Vaskar Saha

Tiina Vesterinen

Doris Steinemann

Amir Enshaei

David Westhead

Pamela Kearns

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