Antje Grosche

Professor

Ludwig-Maximilians-Universität München

Germany

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Antje Grosche is a Professor at Ludwig-Maximilians-Universität München, Germany. Her research areas include neurodegeneration, cellular signaling in Müller cells, and the role of complement factors in retinal health and disease, as evidenced by her recent publications. She focuses on understanding the mechanisms underlying conditions such as Niemann-Pick type C disease and diabetic retinal responses. Her work integrates proteomic analyses with in vivo models to explore Müller cell functionality and their implications in retinal disorders.

Articles (14)

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2024

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2024

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2024

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2024

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2023

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2022

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2021

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2021

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2020

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2020

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2020

Collaborators (8)

Anne Wolf

Lab Head

University of Cologne

GERMANY

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Peter Fuchs

Universität Wien

AUSTRIA

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Paul Gamlin

Professor

University of Alabama, Tuscaloosa

UNITED STATES

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Tobias Straub

Head

Ludwig-Maximilians-Universität München

GERMANY

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Guillaume Blot

Université de Montréal

CANADA

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Christianne Strang

University of Alabama, Tuscaloosa

UNITED STATES

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Nicole Schäfer

University of Regensburg

GERMANY

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Uwe Wolfrum

Johannes Gutenberg Universität Mainz

GERMANY

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Antje Grosche

Research Interests

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Articles (14)

CD44 signaling in Müller cells impacts photoreceptor function and survival in healthy and diseased retinas

Myeloid cell-specific loss of NPC1 in mice recapitulates microgliosis and neurodegeneration in patients with Niemann-Pick type C disease.

Gliosis-dependent expression of complement factor H truncated variants attenuates retinal neurodegeneration following ischemic injury.

The glucocorticoid receptor as a master regulator of the Müller cell response to diabetic conditions in mice.

Retinal regions shape human and murine Müller cell proteome profile and functionality

As in Real Estate, Location Matters: Cellular Expression of Complement Varies Between Macular and Peripheral Regions of the Retina and Supporting Tissues

Expression and subcellular localization of USH1C/harmonin in human retina provides insights into pathomechanisms and therapy

Release of VAMP5-positive extracellular vesicles by retinal Müller glia in vivo

PDGF Receptor Alpha Signaling Is Key for Müller Cell Homeostasis Functions

Proteomic Phenotyping of Stimulated Müller Cells Uncovers Profound Pro-Inflammatory Signaling and Antigen-Presenting Capacity

Sodium Iodate-Induced Degeneration Results in Local Complement Changes and Inflammatory Processes in Murine Retina

IL-1β induces rod degeneration through the disruption of retinal glutamate homeostasis

Cell-Type-Specific Complement Profiling in the ABCA4-/- Mouse Model of Stargardt Disease

The role of Müller cell glucocorticoid signaling in diabetic retinopathy

Collaborators (8)

Anne Wolf

Peter Fuchs

Paul Gamlin

Tobias Straub

Guillaume Blot

Christianne Strang

Nicole Schäfer

Uwe Wolfrum

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