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Asta Zubriene

Senior scientist

Vilnius University

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Research Interests

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Professors in Pharmaceutical Chemistry

Articles (18)

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2026

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2025

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2023

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2023

Collaborators (11)

John Ladbury

Professor and Director of Leeds Centre for Disease Models

University of Leeds

UNITED KINGDOM

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Visvaldas Kairys

senior researcher

Vilnius University

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Gunna Christiansen

Aalborg University

DENMARK

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Andrius Sakalauskas

Senior Scientist

Vilnius University

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Ruta Kananaviciute

Assistant Professor

Vilnius University

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Lucy Kate Ladefoged

Aarhus University

DENMARK

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Zane Kalnina

Unit head, Senior researcher

National Institute of Research and Innovation

LATVIA

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Elena Manakova

senior researcher

Vilnius University

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Lina Baranauskienė

Senior researcher

Vilnius University

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Evaldas Naujalis

Professor

Vilnius University

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Martin Distel

Associate Professor

University of Utah

UNITED STATES

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Asta Zubriene

Research Interests

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Articles (18)

Radiobiological investigations of a [ 212 Pb]Pb-carbonic anhydrase IX-targeting small-molecule ligand in renal cell carcinoma and colorectal cancer models

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

Novel Derivatives of 3-Amino-4-hydroxy-benzenesulfonamide: Synthesis, Binding to Carbonic Anhydrases, and Activity in Cancer Cell 2D and 3D Cultures

Design of Rigid Compounds to Enhance Selectivity for Carbonic Anhydrase IX.

Hiding in plain sight: Optimizing topoisomerase IIα inhibitors into Hsp90β selective binders

First dual inhibitors of human topoisomerase IIα and Hsp90 C-terminal domain inhibit the growth of Ewing sarcoma in vitro and in vivo

Exploration and optimisation of structure-activity relationships of new triazole-based C-terminal Hsp90 inhibitors towards in vivo anticancer potency

High-Affinity NIR-Fluorescent Inhibitors for Tumor Imaging via Carbonic Anhydrase IX

From X-ray crystallographic structure to intrinsic thermodynamics of protein–ligand binding using carbonic anhydrase isozymes as a model system

Comprehensive analysis of resorcinyl-imidazole Hsp90 inhibitor design

Recent advances in computational and experimental protein-ligand affinity determination techniques

Thermal shift assay for protein–ligand dissociation constant determination

Inhibitor binding to metal-substituted metalloenzyme: Sulfonamide affinity for carbonic anhydrase IX

Synthesis and histone deacetylases inhibitory activity of pyrimidine‐based 1,3,4‐oxadiazoles

New Class of Hsp90 C-Terminal Domain Inhibitors with Anti-tumor Properties against Triple-Negative Breast Cancer

Inhibitory effects of fluorinated benzenesulfonamides on insulin fibrillation

PLBD: protein–ligand binding database of thermodynamic and kinetic intrinsic parameters

Screening, Synthesis and Biochemical Characterization of SARS-CoV-2 Protease Inhibitors

Collaborators (11)

John Ladbury

Visvaldas Kairys

Gunna Christiansen

Andrius Sakalauskas

Ruta Kananaviciute

Lucy Kate Ladefoged

Zane Kalnina

Elena Manakova

Lina Baranauskienė

Evaldas Naujalis

Martin Distel

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