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Atsushi Minami

Professor

Tokyo Institute of Technology

Japan

Research Interests

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About

Atsushi Minami is an Associate Professor at Hokkaido University in Japan. His research areas include the biosynthesis of fungal natural products, chemical synthesis, and bioinformatics. Recent articles highlight his work on the total synthesis and stereochemical revision of natural compounds, as well as the exploration of biosynthetic mechanisms in fungi. His contributions significantly advance the understanding of fungal biochemistry and natural products.

Articles (26)

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2020

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2020

Collaborators (15)

Taro Ozaki

Associate Professor

Tohoku University

JAPAN

Atsushi Minami

Research Interests

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Articles (26)

A system of paired polyether epoxide hydrolases enables a mouldable enzyme for consecutive ring cyclization cascades

Structure-guided switching of carbocation quenching in sesquiterpene synthases for accessing aromadendrane and guaiane frameworks

High-Throughput Prediction of Protein–Protein Interactions Uncovers Hidden Molecular Networks in Biosynthetic Gene Clusters

Antifungal Cyclic Peptides Dinemasporins from the Culture of <i>Dinemasporium parastrigosum</i> KT4144

Isolation and Identification of Xanthone, Benzofuran, and Spirolactone Derivatives from <i>Dinemasporium parastrigosum</i> KT4144 and Their Plausible Biosynthetic Pathways

Chain-length preference of trans-acting enoylreductases involved in the biosynthesis of fungal polyhydroxy polyketides

A fungal transcription factor converts a beneficial root endophyte into an anthracnose leaf pathogen

Thermolides D and E: Total Synthesis and Stereochemical Revision

Biochemistry and Chemoinformatics Guided Classification of Hirsutane Sesquiterpenes Isolated from Mushroom

Bioinformatics-Guided Reconstitution of Biosynthetic Machineries of Fungal Eremophilane Sesquiterpenes

Subcellular compartmentalized localization of transmembrane proteins essential for production of fungal cyclic peptide cyclochlorotine

Versatile filamentous fungal host highly-producing heterologous natural products developed by genome editing-mediated engineering of multiple metabolic pathways

A fungal sesquiterpene biosynthesis gene cluster critical for mutualist-pathogen transition in Colletotrichum tofieldiae

Oxidative bicyclic ring system formation involving indole diterpene biosynthesis: Remarkable substrate tolerance of a prenyltransferase and flavoprotein oxidase

Biosynthesis of indole diterpenes: a reconstitution approach in a heterologous host

Controlled Chemical Construction in Nature: Unified Biogenesis Accounting for Synthesis of Fungal Dimeric Anhydrides

Total Biosynthesis of Melleolides from Basidiomycota Fungi: Mechanistic Analysis of the Multifunctional GMC Oxidase Mld7

Heterologous expression of a polyketide synthase ACRTS2 in Aspergillus oryzae produces host-selective ACR toxins: Coproduction of minor metabolites

Recent advances in the biosynthesis of ribosomally synthesized and posttranslationally modified peptides of fungal origin.

Elucidation of Late-Stage Biosynthesis of Phomoidride: Proposal of Cyclization Mechanism Affording Characteristic Nine-Membered Ring of Fungal Dimeric Anhydride

Structure and biosynthesis of the ribosomal lipopeptide antibiotic albopeptins

Biosynthetic machineries of anthraquinones and bisanthraquinones in Talaromyces islandicus

Biosynthetic Studies of Phomopsins Unveil Posttranslational Installation of Dehydroamino Acids by UstYa Family Proteins

Biosynthetic Studies of Phomopsins Unveil Posttranslational Installation of Dehydroamino Acids by UstYa Family Proteins

Biosynthesis of Indole Diterpene Lolitrems: Radical-Induced Cyclization of an Epoxyalcohol Affording a Characteristic Lolitremane Skeleton

Predicting the chemical space of fungal polyketides by phylogeny-based bioinformatics analysis of polyketide synthase-nonribosomal peptide synthetase and its modification enzymes

Collaborators (15)

Taro Ozaki

Hideaki Oikawa

Kei Hiruma

Yoshitaka Moriwaki

Kowit Hengphasatporn

Taro Shiraishi

Hajime Sato

Shusuke Sato

Jun-ichi Maruyama

Kazuya Akimitsu

Jie Zhang

Kenichi Matsuda

Masanobu Uchiyama

Masanori Okamoto

Susumu Mochizuki

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