Atsushi Umemura

Professor

Kyoto Prefectural University of Medicine

Japan

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Atsushi Umemura is a Professor at Kyoto Prefectural University of Medicine in Japan. His research areas include mitochondrial toxicity, early detection of pancreatic cancer, and liver fibrosis treatment. He has published recent articles on topics such as the therapeutic potential of Carfilzomib and the impacts of drug-induced oxidative stress. Prof. Umemura also explores advancements in AI for medical diagnostics and the role of reactive oxygen species in cancer pathophysiology.

Articles (20)

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2025

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2020

Collaborators (4)

Yoshito Itoh

professor

JAPAN

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Kaori Shintani-Ishida

Kyoto Prefectural University of Medicine

JAPAN

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Maria Diaz-Meco

Professor

Weill Cornell Medical College

UNITED STATES

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Misaki Matsumoto

Wakayama Medical University

JAPAN

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Atsushi Umemura

Research Interests

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Articles (20)

Clioquinol induces mitochondrial toxicity in SH‐SY5Y neuroblastoma cells by affecting the respiratory chain complex IV and OPA1 dynamin‐like GTPase

Early detection of pancreatic cancer by comprehensive serum miRNA sequencing with automated machine learning.

Carfilzomib shows therapeutic potential for reduction of liver fibrosis by targeting hepatic stellate cell activation.

Inter-individual variations in circadian misalignment-induced NAFLD pathophysiology in mice

Safety/efficacy of atezolizumab + bevacizumab during anti-platelet/anticoagulation therapy in unresectable hepatocellular carcinoma

Comparison of portal vein hemodynamics with ultrasound-based elastography for the prediction of liver fibrosis in patients with chronic liver disease

Editorial: Impacts of drug-induced oxidative stress

Fibro-Scope V1.0.1: an artificial intelligence/neural network system for staging of nonalcoholic steatohepatitis

Reactive Oxygen Species and NRF2 Signaling, Friends or Foes in Cancer?

Bortezomib is an effective enhancer for chemical probe-dependent superoxide detection

A novel rapid immunoassay of serum type IV collagen 7S for the diagnosis of fibrosis stage of nonalcoholic fatty liver diseases

Artificial intelligence/neural network system for the screening of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis

Honokiol prevents non-alcoholic steatohepatitis-induced liver cancer via EGFR degradation through the glucocorticoid receptor—MIG6 axis

Novel artificial intelligent/neural network system for staging of nonalcoholic steatohepatitis

SOX2 enhances cell survival and induces resistance to apoptosis under serum starvation conditions through the AKT/GSK-3β signaling pathway in esophageal squamous cell carcinoma

The effect of genetic polymorphism in response to body weight reduction in japanese patients with nonalcoholic fatty liver disease

Tyrosine Kinase Inhibitors Stimulate HLA Class I Expression by Augmenting the IFNγ/STAT1 Signaling in Hepatocellular Carcinoma Cells

NRF2 activates growth factor genes and downstream AKT signaling to induce mouse and human hepatomegaly

Attenuated effect of PNPLA3 on hepatic fibrosis by HSD17B13 in Japanese patients with non-alcoholic fatty liver disease

Early tumor shrinkage as a predictive factor for outcomes in hepatocellular carcinoma patients treated with lenvatinib: A multicenter analysis

Collaborators (4)

Yoshito Itoh

Kaori Shintani-Ishida

Maria Diaz-Meco

Misaki Matsumoto

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