Babak Razani

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Washington University

United States

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Recent Grants

Grant: Close

Harnessing macrophage lysosomal lipid metabolism in obesity-associated diseases

Open Date: 2022-07-04

Close Date: 2026-06-30

Grant: Open

Dissecting the Impact of Dietary Protein on Macrophage mTOR Signaling and Atherosclerosis

Open Date: 2022-04-01

Close Date: 2027-03-31

Grant: Close

Harnessing the autophagy-lysosomal biogenesis response in macrophages to treat obesity and insulin resistance

Open Date: 2018-01-01

Close Date: 2020-12-31

Grant: Close

Harnessing the Autophagy-Lysosomal Biogenesis Response in Macrophages to Treat Atherosclerosis

Open Date: 2018-01-01

Close Date: 2021-12-31

Grant: Close

THE ROLE OF MACROPHAGE LYSOSOMAL BIOGENESIS IN ATHEROSCLEROSIS

Open Date: 2014-11-04

Close Date: 2019-10-31

Articles (19)

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Collaborators (12)

Alexxai Kravitz

Associate Professor

Washington University in St. Louis

UNITED STATES

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Slava Epelman

Associate Professor

University of Toronto

CANADA

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Georges Doumet HELOU

Junior Professor of Immunology

Sorbonne Université Faculté de Médecine

FRANCE

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Julie Van

University of Toronto

CANADA

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Nicolas Manel

PSL Research University

FRANCE

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Irfan Lodhi

Washington University in St. Louis

UNITED STATES

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Jaehyung Cho

Professor

Washington University in St. Louis

UNITED STATES

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Giuseppe Danilo Norata

University of Milan

ITALY

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Marina Terekhova

Washington University in St. Louis

UNITED STATES

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Michael B Wheeler

University of Toronto

CANADA

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Yousang Gwack

Professor

University of California, Los Angeles

UNITED STATES

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Jin-Moo Lee

Professor

Washington University School of Medicine

UNITED STATES

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Babak Razani

Research Interests

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Recent Grants

Articles (19)

Neutrophil CRACR2A Promotes Neutrophil Recruitment in Sterile Inflammation and Ischemic Stroke

Reduced circulating sphingolipids and CERS2 activity are linked to T2D risk and impaired insulin secretion.

Lysosomes in the immunometabolic reprogramming of immune cells in atherosclerosis

Amino Acid Metabolism and Atherosclerotic Cardiovascular Disease

Glutamine–glutamate imbalance in the pathogenesis of cardiovascular disease

Enhancing autophagy in CD11c+ antigen-presenting cells as a therapeutic strategy for acute respiratory distress syndrome

A Critical Role for ERO1α in Arterial Thrombosis and Ischemic Stroke

Steatosis Drives Monocyte-derived Macrophage Accumulation in Human Metabolic Dysfunction-Associated Fatty Liver Disease

Lipid-laden foam cells in the pathology of atherosclerosis: shedding light on new therapeutic targets

TMEM135 links peroxisomes to the regulation of brown fat mitochondrial fission and energy homeostasis

metGWAS 1.0: an R workflow for network-driven over-representation analysis between independent metabolomic and meta-genome-wide association studies

Spatially Resolved Metabolites in Stable and Unstable Human Atherosclerotic Plaques Identified by Mass Spectrometry Imaging

Loss of Macrophage mTORC2 Drives Atherosclerosis via FoxO1 and IL-1β Signaling.

Use of acidic nanoparticles to rescue macrophage lysosomal dysfunction in atherosclerosis

Evaluation of mTORC1 signaling in mouse atherosclerotic macrophages by flow cytometry and immunofluorescence

PCSK9 Pleiotropism: In the Same Vein as Statins

Subcutaneous Adipose Tissue Metabolic Function and Insulin Sensitivity in People With Obesity

MED19 Regulates Adipogenesis and Maintenance of White Adipose Tissue Mass by Mediating PPARγ-Dependent Gene Expression.

Inflammasomes: a preclinical assessment of targeting in atherosclerosis

Collaborators (12)

Alexxai Kravitz

Slava Epelman

Georges Doumet HELOU

Julie Van

Nicolas Manel

Irfan Lodhi

Jaehyung Cho

Giuseppe Danilo Norata

Marina Terekhova

Michael B Wheeler

Yousang Gwack

Jin-Moo Lee

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