Benjamin Morehouse

Assistant Professor

University of California, Irvine

United States

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Dr. Benjamin Morehouse is an Assistant Professor at the University of California, Irvine, specializing in bacteriology and innate immunity. His recent research explores the mechanisms of viral defense in bacteria, including the role of amyloids and pattern recognition receptors. Dr. Morehouse's work contributes significantly to understanding phage-bacterial interactions and the evolutionary origins of immune responses.

Articles (13)

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2025

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2025

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2024

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2023

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2023

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2023

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2022

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2022

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2022

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2021

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2020

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2020

Collaborators (4)

Arnau Sebé-Pedrós

Catalan Institution for Research and Advanced Studies (ICREA)

SPAIN

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Nora McNamara-Bordewick

Dana-Farber Cancer Institute

UNITED STATES

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Samuel Hobbs

Dana-Farber Cancer Institute

UNITED STATES

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Sichen Shao

Associate Professor

Harvard Medical School

UNITED STATES

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Benjamin Morehouse

Research Interests

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Articles (13)

Amyloids in bacterial antiphage defence

A human homolog of SIR2 antiphage proteins mediates immunity via the TLR pathway

An OLD protein teaches us new tricks: prokaryotic antiviral defense

Say YES to single-gene lysis!

cGLRs are a diverse family of pattern recognition receptors in innate immunity.

Phage defense origin of animal immunity.

Viruses inhibit TIR gcADPR signalling to overcome bacterial defence.

Cryo-EM structure of an active bacterial TIR-STING filament complex.

Phage anti-CBASS and anti-Pycsar nucleases subvert bacterial immunity.

Cyclic CMP and cyclic UMP mediate bacterial immunity against phages.

cGAS-like receptors sense RNA and control 3'2'-cGAMP signalling in Drosophila.

CBASS Immunity Uses CARF-Related Effectors to Sense 3′–5′- and 2′–5′-Linked Cyclic Oligonucleotide Signals and Protect Bacteria from Phage Infection

STING cyclic dinucleotide sensing originated in bacteria

Collaborators (4)

Arnau Sebé-Pedrós

Nora McNamara-Bordewick

Samuel Hobbs

Sichen Shao

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