Benjamin Ruf

Head of Research Group

University of Tübingen

Germany

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About

Dr. Benjamin Ruf is the Head of Research Group at the University of Tübingen, Germany. His research interests focus on the tumor microenvironment, immune response in liver cancer, and the interactions between immune checkpoint inhibitors and metabolic conditions. Recent publications include studies on the effects of PexaVec in metastatic colorectal cancer, the role of metformin in enhancing T-cell responses, and investigating the dynamics of innate lymphoid cells in hepatocellular carcinoma.

Articles (10)

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2023

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2022

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2022

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2022

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2022

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2022

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2022

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2022

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2022

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2022

Collaborators (5)

Yaron Rotman

National Institute of Diabetes and Digestive and Kidney Diseases Laboratory of Molecular Biology

UNITED STATES

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Firouzeh Korangy

National Institutes of Health

UNITED STATES

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Simon Wabitsch

Medical University of Vienna

AUSTRIA

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Juliane S. Walz

University Hospital Tübingen

GERMANY

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Tim Greten

National Institutes of Health

UNITED STATES

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Benjamin Ruf

Research Interests

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Articles (10)

Phase I/II study of PexaVec in combination with immune checkpoint inhibition in refractory metastatic colorectal cancer

NAFLD indirectly impairs antigen-specific CD8+ T cell immunity against liver cancer in mice

Metformin treatment rescues CD8+ T-cell response to immune checkpoint inhibitor therapy in mice with NAFLD

Platelets control liver tumor growth through P2Y12-dependent CD40L release in NAFLD.

The tumour microenvironment shapes innate lymphoid cells in patients with hepatocellular carcinoma

The tumour microenvironment shapes innate lymphoid cells in patients with hepatocellular carcinoma

Checkpoint Inhibitors Modulate Plasticity of Innate Lymphoid Cells in Peripheral Blood of Patients With Hepatocellular Carcinoma

Chromoendoscopy in Combination with Random Biopsies for Patients with Pathogenic CDH1 Mutations Undergoing Endoscopic Surveillance

Chromoendoscopy in Combination with Random Biopsies for Patients with Pathogenic CDH1 Mutations Undergoing Endoscopic Surveillance

Highly multiplexed spatial analysis of the HCC tumor immune microenvironment using CODEX imaging

Collaborators (5)

Yaron Rotman

Firouzeh Korangy

Simon Wabitsch

Juliane S. Walz

Tim Greten

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