Benjamin Wylie

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Associate Professor

Texas Tech University

United States

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About

Benjamin Wylie is an Associate Professor at Texas Tech University in the United States. His research focuses on the structural plasticity of chemokine receptors, protein-lipid interactions, and the dynamic properties of membrane proteins. His recent publications include studies on cancer-associated mutations in CCR3 and the cooperative gating of K+ channels. He is also investigating the effects of cholesterol on receptor conformations and the behavior of diazo-functionalized compounds.

Recent Grants

Grant: Close

Functional Interplay of Lipid Membrane Components: Activation, Inhibition, and Raft Formation

Open Date: 2017-08-10

Close Date: 2023-07-31

Grant: Close

Structural and Functional Studies of Potassium Channels by Solid-State NMR

Open Date: 2009-04-01

Close Date: 2012-03-31

Grant: Open

MEMBRANES OF THE DENTAL PATHOGEN STREPTOCOCCUS MUTANS

Open Date: 1986-03-01

Close Date: 2027-06-30

Articles (15)

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2025

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2024

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2023

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2022

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2022

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2022

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2022

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2021

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2021

Collaborators (2)

Kristin Hutchins

Associate Professor of Chemistry

University of Missouri

UNITED STATES

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Markus Weingarth

NETHERLANDS

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Benjamin Wylie

Research Interests

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About

Recent Grants

Articles (15)

An in silico framework to visualize how cancer‐associated mutations influence structural plasticity of the chemokine receptor CCR3

Cooperative Gating of a K+ Channel by Unmodified Biological Anionic Lipids Viewed by Solid-State NMR Spectroscopy

Coordination of bilayer properties by an inward-rectifier K+ channel is a cooperative process driven by protein-lipid interaction

Colossal Anisotropic Thermal Expansion in a Diazo‐Functionalized Compound with Switchable Solid‐State Behavior

Colossal Anisotropic Thermal Expansion in a Diazo‐Functionalized Compound with Switchable Solid‐State Behavior

Cholesterol Biases the Conformational Landscape of the Chemokine Receptor CCR3: A MAS SSNMR-Filtered Molecular Dynamics Study

Cardiolipin occupancy profiles of YidC paralogs reveal the significance of respective TM2 helix residues in determining paralog-specific phenotypes

Strategies for acquisition of resonance assignment spectra of highly dynamic membrane proteins: a GPCR case study

Mutational Insight into Allosteric Regulation of Kir Channel Activity

2H,13C-Cholesterol for Dynamics and Structural Studies of Biological Membranes

A Cholesterol Dimer Stabilizes the Inactivated State of an Inward‐Rectifier Potassium Channel

A Cholesterol Dimer Stabilizes the Inactivated State of an Inward‐Rectifier Potassium Channel

Spectroscopic signatures of bilayer ordering in native biological membranes

Catalyst-Enabled In Situ Linkage Reduction in Imine Covalent Organic Frameworks

Cholesterol Is a Dose-Dependent Positive Allosteric Modulator of CCR3 Ligand Affinity and G Protein Coupling

Collaborators (2)

Kristin Hutchins

Markus Weingarth

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