Brahim Benyahia

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Professor

Loughborough University

United Kingdom

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About

Professor Brahim Benyahia is a faculty member at Loughborough University in the United Kingdom. His research primarily focuses on the application of data-driven approaches in digital design, optimization of chemical processes, and sustainability assessments in pharmaceutical manufacturing. Notable recent contributions include works on deep reinforcement learning for flow chemistry and computer-aided retrosynthesis for greener synthesis of pharmaceutical ingredients.

Recent Grants

Grant: Close

SusPharma - Merging Chemistry Technologies for Sustainable Pharmaceutical Design and Development.

Open Date: 2022-09-01

Close Date: 2025-08-01

Grant: Close

Made Smarter Innovation - Digital Medicines Manufacturing Research Centre: Levelling up the UK’s digital medicine manufacturing capabilities

Open Date: 2021-09-01

Close Date: 2025-03-01

Grant: Close

Novel, cost-effective, stand-alone integrated portable microfluidic platform for self-optimised plug-and-play screening and production.

Open Date: 2019-11-01

Close Date: 2020-03-01

Grant: Close

ARTICULAR: ARtificial inTelligence for Integrated ICT-enabled pharmaceUticaL mAnufactuRing

Open Date: 2018-06-30

Close Date: 2022-06-29

Grant: Close

Linking synthesis to crystallisation - counter current liquid - liquid extraction

Open Date: 2018-05-01

Close Date: 2018-12-01

Articles (17)

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2025

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2024

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2024

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2023

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2022

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2022

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2021

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2020

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2020

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2020

Collaborators (6)

Chris D. Rielly

Loughborough University

UNITED KINGDOM

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Huaiyu Yang

Senior Lecturer / Associate professor

Loughborough University

UNITED KINGDOM

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Lauren E. Hatcher

UNITED KINGDOM

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Marijana Dragosavac

Senior Lecturer

Loughborough University

UNITED KINGDOM

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Gianvito Vilé

Associate Professor

Politecnico di Milano

ITALY

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Hemaka Bandulasena

Reader in Chemical Engineering

Loughborough University

UNITED KINGDOM

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Brahim Benyahia

Research Interests

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About

Recent Grants

Articles (17)

Digital design and optimization of the integrated synthesis and crystallization process using data‐driven approaches

A comprehensive framework for model evaluation and refinement using MBDoE estimability and structural identifiability: application to a crystallization process

Deep Reinforcement Learning-Based Self-Optimization of Flow Chemistry

Design and optimization of a shared synthetic route for multiple active pharmaceutical ingredients through combined computer aided retrosynthesis and flow chemistry

Sustainability and Techno-Economic Assessment of Batch and Flow Chemistry in Seven Industrial Pharmaceutical Processes

SolECOs: a data-driven platform for sustainable and comprehensive solvent selection in pharmaceutical manufacturing

ESTAN—A toolbox for standardized and effective global sensitivity-based estimability analysis

Single and Multiobjective Shutdown Optimization of a Multistage Continuous Crystallizer

A framework for systematic crystal shape tuning – Case of Lovastatin's needle-shaped crystals

Computer-Aided Retrosynthesis for Greener and Optimal Total Synthesis of a Helicase-Primase Inhibitor Active Pharmaceutical Ingredient

Production and Tuning of Spherical Agglomerates of Benzoic Acid Using Membrane Dispersion Systems

Use of Wet Milling Combined with Temperature Cycling to Minimize Crystal Agglomeration in a Sequential Antisolvent–Cooling Crystallization

Optimal start-up strategies of a combined cooling and antisolvent multistage continuous crystallization process

Experimental and Computational Analysis of Mixing Inside Droplets for Microfluidic Fabrication of Gold Nanoparticles

Systematic Model-Based Steady State and Dynamic Optimization of Combined Cooling and Antisolvent Multistage Continuous Crystallization Processes

Tuning Morphology in Active Pharmaceutical Ingredients: Controlling the Crystal Habit of Lovastatin through Solvent Choice and Non-Size-Matched Polymer Additives

CO2 capture performance and environmental impact of copolymers of ethylene glycol dimethacrylate with acrylamide, methacrylamide and triallylamine

Collaborators (6)

Chris D. Rielly

Huaiyu Yang

Lauren E. Hatcher

Marijana Dragosavac

Gianvito Vilé

Hemaka Bandulasena

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