Brahim Chaqour

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Director of Research, Lecturer

University of Pennsylvania

United States

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About

Brahim Chaqour is the Director of Research and a Lecturer at the University of Pennsylvania, USA. His research focuses on cell signaling mechanisms, gene therapy technologies, and the neuroprotective strategies for retinal ganglion cells. Recent publications highlight his contributions to understanding cell line authentication, mitochondrial influences in neurodegeneration, and advancements in gene delivery systems for vision-related therapies.

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Markers of Angiogenesis and Fibrosis

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Articles (13)

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2025

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2025

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2025

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2023

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2023

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2023

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2022

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2022

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2022

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2021

Collaborators (2)

Ulf Smith

University of Gothenburg, Sahlgrenska Academy

SWEDEN

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Lester Lau

Professor

University of Chicago

UNITED STATES

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Brahim Chaqour

Research Interests

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Recent Grants

Articles (13)

Cell line authentication and validation is a key requirement for Journal of Cell Communication and Signaling publications

Unlocking New Frontiers in Cell Signaling and Communication and Fostering New Collaborative Interactions and Scientific Initiatives: Lessons Learned from the International Cellular Communication Network Society (ICCNS) Workshop

Mitochondrial Uncoupler, 2,4-Dinitrophenol, Reduces Spinal Cord Paralysis and Retinal Ganglion Cell Loss in the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis

AAV2 vector optimization for retinal ganglion cell-targeted delivery of therapeutic genes

Report on the 11th international workshop on the CCN family of genes, Nice, October 20–24, 2022

CCN–Hippo YAP signaling in vision and its role in neuronal, glial and vascular cell function and behavior

Emerging Gene Therapy Technologies for Retinal Ganglion Cell Neuroprotection.

Cell-Specific Expression of Human SIRT1 by Gene Therapy Reduces Retinal Ganglion Cell Loss Induced by Elevated Intraocular Pressure.

Atomic Force Microscopy-Based Measurements of Retinal Microvessel Stiffness in Mice with Endothelial-Specific Deletion of CCN1.

Selective Upregulation of SIRT1 Expression in Retinal Ganglion Cells by AAV-Mediated Gene Delivery Increases Neuronal Cell Survival and Alleviates Axon Demyelination Associated with Optic Neuritis

Role of Erythropoietin Receptor Signaling in Macrophages or Choroidal Endothelial Cells in Choroidal Neovascularization

Repeat Brn3a immunolabeling rescues faded staining and improves detection of retinal ganglion cells.

The CCN2/CTGF interactome: an approach to understanding the versatility of CCN2/CTGF molecular activities

Collaborators (2)

Ulf Smith

Lester Lau

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