Brandon Coombes

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Assistant Professor of Biostatistics

Mayo Clinic

United States

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Brandon Coombes is an Assistant Professor of Biostatistics at Mayo Clinic in the United States. His research areas include the clinical associations of treatment resistance in depression, the genetic contributions to medical comorbidities in bipolar disorder, and the effects of medications on youth with ADHD. Recent articles highlight his work on symptom severity across racial groups and the molecular mechanisms driving alcohol craving.

Recent Grants

Grant: Close

2/4: Leveraging EHR-linked biobanks for deep phenotyping, polygenic risk score modeling, and outcomes analysis in psychiatric disorders

Open Date: 2019-09-05

Close Date: 2024-05-31

Articles (17)

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Marin Veldic

Associate Professor

Mayo Clinic

UNITED STATES

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Balwinder Singh

Assistant Professor

Mayo Clinic Rochester

UNITED STATES

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Brandon Coombes

Research Interests

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About

Recent Grants

Articles (17)

Symptom Severity and Treatment Needs Among Racial Groups Seeking Treatment at a Mood Outcomes Program

Measuring the exposome in bipolar disorder

Clinical and genetic contributions to medical comorbidity in bipolar disorder: a study using electronic health records-linked biobank data

Risk of Newly Diagnosed Psychotic Symptoms in Youth Receiving Medications for Attention-Deficit/Hyperactivity Disorder

Molecular mechanisms involved in alcohol craving, IRF3, and endoplasmic reticulum stress: a multi-omics study

Pharmacogenomic overlap between antidepressant treatment response in major depression & antidepressant associated treatment emergent mania in bipolar disorder

Clinical associations with treatment resistance in depression: An electronic health record study

Phenotypic distinctions in depression and anxiety: a comparative analysis of comorbid and isolated cases

Antidepressants that increase mitochondrial energetics may elevate risk of treatment-emergent mania

The genetic contribution to the comorbidity of depression and anxiety: a multi-site electronic health records study of almost 178 000 people

Pharmacotherapy exposure as a marker of disease complexity in bipolar disorder: Associations with clinical & genetic risk factors

Whole Genome Analysis of Venous Thromboembolism: the Trans-Omics for Precision Medicine Program

Polygenic prediction of bipolar disorder in a Latin American sample

Single cell transcriptomics reveals distinct transcriptional responses to oxycodone and buprenorphine by iPSC-derived brain organoids from patients with opioid use disorder

Genetic contributions to alcohol use disorder treatment outcomes: a genome-wide pharmacogenomics study

TCF7L2 lncRNA: a link between bipolar disorder and body mass index through glucocorticoid signaling

Genetic contributions to bipolar disorder: current status and future directions

Collaborators (8)

Susannah Tye

William Bobo

Man Choi Ho

Olusola Ajilore

Joanna Biernacka

Ming-Huei Chen

Marin Veldic

Balwinder Singh

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