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Bård Helge Hoff

Professor

Norges teknisk-naturvitenskapelige universitet

Norway

Research Interests

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Professors in Norway Professors in Organic Chemistry Organic Chemistry professors in Norway

About

Professor Bård Helge Hoff is a faculty member at Norges teknisk-naturvitenskapelige universitet in Norway. His research focuses on the design and synthesis of pyrrolopyrimidine and pyridine-based compounds, particularly as CSF1R inhibitors, and the structural analysis of guanidines. He has contributed significantly to advancements in synthetic methodologies and the study of antibiotic candidates against bacterial resistance.

Articles (20)

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Bård Helge Hoff

Research Interests

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Articles (20)

Evaluating Triazole-Substituted Pyrrolopyrimidines as CSF1R Inhibitors

Design and Synthesis of Pyridine-Based Pyrrolo[2,3-d]pyrimidine Analogs as CSF1R Inhibitors: Molecular Hybridization and Scaffold Hopping Approach

X-ray Structure of Eleven New N,N′-Substituted Guanidines: Effect of Substituents on Tautomer Structure in the Solid State

Synthetic Routes to 2-aryl-1H-pyrrolo[2,3-b]pyridin-4-amines: Cross-Coupling and Challenges in SEM-Deprotection

Promotion of Water as Solvent in Amination of 4-Chloropyrrolopyrimidines and Related Heterocycles under Acidic Conditions

Pyrrolopyrimidine based CSF1R inhibitors: Attempted departure from Flatland

Improved Synthetic Methodology, Substrate Scope and X‐ray Crystal Structure for N, N’‐disubstituted Guanidines

Strategies for successful Suzuki-Miyaura cross-couplings with thienylboronic acids: From model studies to dye structures

Directed Lithiation of Protected 4-Chloropyrrolopyrimidine: Addition to Aldehydes and Ketones Aided by Bis(2-dimethylaminoethyl)ether

Synthesis and Development of Highly Selective Pyrrolo[2,3-<i>d</i>]pyrimidine CSF1R Inhibitors Targeting the Autoinhibited Form

Activation of multiple stress responses in Staphylococcus aureus substantially lowers the minimal inhibitory concentration when combining two novel antibiotic drug candidates

A highly selective purine-based inhibitor of CSF1R potently inhibits osteoclast differentiation

Halogenated Pyrrolopyrimidines with Low MIC on Staphylococcus aureus and Synergistic Effects with an Antimicrobial Peptide

Effect of seven different terthiophene π-spacers on dye performance in dye-sensitized solar cells

Adamantyl Side Chains as Anti‐Aggregating Moieties in Dyes for Dye‐Sensitized Solar Cells

Synthetic Efforts to Investigate the Effect of Planarizing the Triarylamine Geometry in Dyes for Dye-Sensitized Solar Cells

Synthesis and in vitro evaluation of a novel thienopyrimidine with phototoxicity towards rat glioma F98 cells

Scalable Fabrication of Metallic Nanogaps at the Sub‐10 nm Level

Synthesis and Evaluation of Fused Pyrimidines as E. coli Thymidylate Monophosphate Kinase Inhibitors

Synthetic Strategies towards Imidazopyridinones and 7‐Azaoxindoles and their Evaluation as Antibacterial Agents

Collaborators (6)

Eirik Sundby

Torkild Visnes

Odd Reidar Gautun

Per Bruheim

John de Mello

Marit Otterlei

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