Brendan Harley

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University of Illinois at Urbana-Champaign

United States

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About

Brendan Harley is a Professor at the University of Illinois at Urbana-Champaign, USA. His research focuses on biomaterials and tissue engineering, with recent articles exploring the interaction of mesenchymal stem cells with various scaffolds, the impact of hypoxia on bone marrow environments, and mechanisms of glioblastoma invasion. He is particularly interested in the applications of hydrogels in cell encapsulation and the immune response in tissue regeneration.

Recent Grants

Grant: Close

Biomimetic hydrogel niches to study the malignant phenotype of glioblastoma multiforme

Open Date: 2016-03-17

Close Date: 2021-02-28

Grant: Close

EAGER: Biomanufacturing the hematopoietic stem cell niche

Open Date: 2015-09-01

Close Date: 2017-08-31

Grant: Close

Label-free interrogation of heterogeneities in HSC fate decision signatures

Open Date: 2015-04-01

Close Date: 2017-01-31

Grant: Close

Gradient Biomaterials to Investigate Niche Regulation of Hematopoiesis

Open Date: 2014-08-01

Close Date: 2019-07-31

Grant: Close

Multi-scale PCL-collagen composites for large bone defect repair

Open Date: 2014-07-01

Close Date: 2016-06-01

Articles (20)

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2021

Collaborators (9)

Marley Dewey

Assistant Professor

University of California, Santa Barbara

UNITED STATES

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Mai Ngo

Assistant Professor

University of Wisconsin-Madison

UNITED STATES

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Isha Mutreja

University of Minnesota

UNITED STATES

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Megan Killian

University of Michigan

UNITED STATES

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Sara Pedron Haba

University of Illinois at Urbana-Champaign

UNITED STATES

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Vasiliki Kolliopoulos

Rice University

UNITED STATES

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Ana Mora-Boza

Georgia Institute of Technology

UNITED STATES

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Mary L. Kraft

University of Illinois at Urbana-Champaign

UNITED STATES

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Noreen Hickok

Professor

Thomas Jefferson University

UNITED STATES

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Brendan Harley

Research Interests

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About

Recent Grants

Articles (20)

Mesenchymal stem cell activity across a graded scaffold-hydrogel composite biomaterial for tendon-to-bone enthesis repair

Crosstalk between macrophages and mesenchymal stem cells shape patterns of osteogenesis and immunomodulation in mineralized collagen scaffolds

Granular Hydrogels as Brittle Yield Stress Fluids

Matrix Tropism Influences Endometriotic Cell Attachment Patterns

Influence of Hypoxia on a Biomaterial Model of the Bone Marrow Perivascular Niche

Glioblastoma drives protease-independent extracellular matrix invasion of microglia

Donor Sex and Passage Conditions Influence MSC Osteogenic Response in Mineralized Collagen Scaffolds

Gelatin maleimide microgels for hematopoietic progenitor cell encapsulation

Hyaluronic Acid Influences Amino Acid Metabolism via Differential L‐Type Amino Acid Transporter 1 Expression in the U87‐Malignant Glioma Cell Line

Acquired Temozolomide Resistance Instructs Patterns of Glioblastoma Behavior in Gelatin Hydrogels

Evaluation of bacterial attachment on mineralized collagen scaffolds and addition of manuka honey to increase mesenchymal stem cell osteogenesis

Inflammatory Licensed hMSCs Exhibit Enhanced Immunomodulatory Capacity in a Biomaterial Mediated Manner

Perivascular Stromal Cells Instruct Glioblastoma Invasion, Proliferation, and Therapeutic Response within an Engineered Brain Perivascular Niche Model

Growing Pains: The Need for Engineered Platforms to Study Growth Plate Biology

Role of Extracellular Matrix Biomolecules on Endometrial Epithelial Cell Attachment and Cytokeratin 18 Expression on Gelatin Hydrogels

Identification of the Differentiation Stages of Living Cells from the Six Most Immature Murine Hematopoietic Cell Populations by Multivariate Analysis of Single-Cell Raman Spectra

Effects of Pregnancy-Specific Glycoproteins on Trophoblast Motility in Three-Dimensional Gelatin Hydrogels

Engineered Tissue Models to Replicate Dynamic Interactions within the Hematopoietic Stem Cell Niche

Hydrogels Containing Gradients in Vascular Density Reveal Dose‐Dependent Role of Angiocrine Cues on Stem Cell Behavior

Microphysiological systems to study tumor-stroma interactions in brain cancer

Collaborators (9)

Marley Dewey

Mai Ngo

Isha Mutreja

Megan Killian

Sara Pedron Haba

Vasiliki Kolliopoulos

Ana Mora-Boza

Mary L. Kraft

Noreen Hickok

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