Brent Scott

Assistant Professor

College of William and Mary

United States

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About

Brent Scott is an Assistant Professor at the College of William & Mary in the United States. His research primarily focuses on the mechanics and kinetics of myosin, including the interactions between actomyosin and regulated thin filaments. Recent articles authored by him explore topics such as the load dependence of phosphate binding and molecular mechanisms behind force generation in muscle proteins.

Articles (7)

Year:

2025

Year:

2024

Year:

2023

Year:

2023

Year:

2021

Year:

2020

Year:

2020

Collaborators (2)

Michael Greenberg

Associate Professor

Washington University School of Medicine

UNITED STATES

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Xiaorong Liu

University of Michigan

UNITED STATES

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Brent Scott

Research Interests

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Articles (7)

Characterizing the concentration and load dependence of phosphate binding to rabbit fast skeletal actomyosin

Modeling thick filament activation suggests a molecular basis for force depression

Single-molecule mechanics and kinetics of cardiac myosin interacting with regulated thin filaments

A mutation in switch I alters the load-dependent kinetics of myosin Va

Myosin's powerstroke occurs prior to the release of phosphate from the active site

Positional Isomers of a Non-Nucleoside Substrate Differentially Affect Myosin Function

FRET and optical trapping reveal mechanisms of actin activation of the power stroke and phosphate release in myosin V

Collaborators (2)

Michael Greenberg

Xiaorong Liu

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