Brett Pickett

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Assistant Professor

Brigham Young University

United States

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About

Dr. Brett Pickett is an Assistant Professor at Brigham Young University in the United States. His research focuses on transcriptomic analysis and mechanisms related to B-cell acute lymphoblastic leukemia (B-ALL), preeclampsia, and cancer, particularly in the context of gene targets and therapeutic implications. Recent publications include studies on the effects of environmental exposures on placental health and immune responses during viral infections.

Recent Grants

Grant: Close

A protein-based method to distinguish seroprevalence in humans for multiple mosquito-borne Flaviviruses

Open Date: 2016-10-01

Close Date: 2018-09-01

Grant: Close

J. Craig Venter Institute (JCVI) Genomic Center for Infectious Diseases (GCID)

Open Date: 2014-04-01

Close Date: 2019-03-01

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Collaborators (9)

Anirban Chakraborty

Assistant Professor

University of Idaho

UNITED STATES

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Paul R. Reynolds

Brigham Young University

UNITED STATES

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Claudia M. Tellez Freitas

Assistant Professor

Roseman University of Health Sciences South Jordan Campus

UNITED STATES

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Juan Arroyo

Brigham Young University

UNITED STATES

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Javier Ochoa-Repáraz

Assistant Professor

Boise State University

UNITED STATES

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K. Scott Weber

Brigham Young University

UNITED STATES

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Julianne Grose

Professor

Brigham Young University

UNITED STATES

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Norberto Gonzalez-Juarbe

University of Maryland at College Park

UNITED STATES

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Sanjay Vashee

Associate Professor

J. Craig Venter Institute

UNITED STATES

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Brett Pickett

Research Interests

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About

Recent Grants

Articles (25)

Histone-, Receptor-, and Integrin-Related Gene Products and ADAM28 as Relevant to B-Cell Acute Lymphoblastic Leukemia (B-ALL)

Reversing Preeclampsia Pathology: AXL Inhibition Restores Mitochondrial Function and ECM Balance

Transcriptomic Insights into Gas6-Induced Placental Dysfunction: Gene Targets for Preeclampsia Therapy

Turkey B Cell Transcriptome Profile During Turkey Hemorrhagic Enteritis Virus (THEV) Infection Highlights Upregulated Apoptosis and Breakdown Pathways That May Mediate Immunosuppression

Comparison of B-Cell Lupus and Lymphoma Using a Novel Immune Imbalance Transcriptomics Algorithm Reveals Potential Therapeutic Targets

Characterizing the splice map of Turkey Hemorrhagic Enteritis Virus.

A summary of the main themes and findings presented at the ASM Intermountain Branch meeting (2024).

Secondary Analysis of Human Bulk RNA-Seq Dataset Suggests Potential Mechanisms for Letrozole Resistance in Estrogen-Positive (ER+) Breast Cancer

Different Lengths of Gestational Exposure to Secondhand Smoke or e-Cigarette Vapor Induce the Development of Placental Disease Symptoms

Availability of Receptors for Advanced Glycation End-Products (RAGE) Influences Differential Transcriptome Expression in Lungs from Mice Exposed to Chronic Secondhand Smoke (SHS)

Genomic Analyses of Major SARS-CoV-2 Variants Predicting Multiple Regions of Pathogenic and Transmissive Importance

Secondary Transcriptomic Analysis of Triple-Negative Breast Cancer Reveals Reliable Universal and Subtype-Specific Mechanistic Markers

Transcriptomics secondary analysis of severe human infection with SARS-CoV-2 identifies gene expression changes and predicts three transcriptional biomarkers in leukocytes.

Diversity and conservation of the genome architecture of phages infecting the Alphaproteobacteria.

Monolithic affinity columns in 3D printed microfluidics for chikungunya RNA detection.

Association between Religious Beliefs and HPV Vaccination Attitudes among College Students

Comparative meta-analysis of host transcriptional response during Streptococcus pneumoniae carriage or infection.

Joint Secondary Transcriptomic Analysis of Non-Hodgkin's B-Cell Lymphomas Predicts Reliance on Pathways Associated with the Extracellular Matrix and Robust Diagnostic Biomarkers.

Comparison of Intracellular Transcriptional Response of NHBE Cells to Infection with SARS-CoV-2 Washington and New York Strains.

Analyzing the impact of a real-life outbreak simulator on pandemic mitigation: An epidemiological modeling study.

Mutation in Hemagglutinin Antigenic Sites in Influenza A pH1N1 Viruses from 2015-2019 in the United States Mountain West, Europe, and the Northern Hemisphere.

Characterization of Staphylococcus aureus biofilms via crystal violet binding and biochemical composition assays of isolates from hospitals, raw meat, and biofilm-associated gene mutants.

Meta-Analysis of Two Human RNA-seq Datasets to Determine Periodontitis Diagnostic Biomarkers and Drug Target Candidates

SnakeWRAP: a Snakemake workflow to facilitate automated processing of metagenomic data through the metaWRAP pipeline

Chikungunya virus time course infection of human macrophages reveals intracellular signaling pathways relevant to repurposed therapeutics.

Collaborators (9)

Anirban Chakraborty

Paul R. Reynolds

Claudia M. Tellez Freitas

Juan Arroyo

Javier Ochoa-Repáraz

K. Scott Weber

Julianne Grose

Norberto Gonzalez-Juarbe

Sanjay Vashee

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