Brian Gulbransen

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Assistant Professor of Neuroscience

Michigan State University

United States

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About

Brian Gulbransen is an Assistant Professor of Neuroscience at Michigan State University, USA. His research focuses on the enteric nervous system and its role in gastrointestinal health and disease, as evidenced by his recent articles on enteric glia, purinergic signaling, and neuroimmune interactions. His work explores various aspects of enteric neuropathy, dysmotility, and the implications for conditions such as Clostridioides difficile infection and Parkinson’s disease.

Recent Grants

Grant: Close

Role of enteric glia in the death of neurons during gut inflammation

Open Date: 2015-07-15

Close Date: 2020-04-30

Grant: Close

Role of enteric glia in the death of neurons during gut inflammation

Open Date: 2015-07-15

Close Date: 2020-04-30

Grant: Close

Role of enteric glial cells in the initiation of neuron death in Crohn's disease.

Open Date: 2015-07-01

Close Date: 2018-06-01

Grant: Close

Role of enteric glial cells in the initiation of neuron death in Crohn’s disease

Open Date: 2015-07-01

Close Date: 2018-06-30

Grant: Close

Mechanistic basis of antioxidant-mediated neuroprotection in inflammatory bowel disease: role of enteric glia

Open Date: 2014-01-01

Close Date: 2014-12-01

Articles (24)

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2021

Collaborators (1)

Stephanie W. Watts

Michigan State University

UNITED STATES

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Brian Gulbransen

Research Interests

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About

Recent Grants

Articles (24)

Enteric glia and purinergic signaling in health and disease

Enteric glial S100B controls rhythmic colonic functions by regulating excitability and specificity in gut motor neurocircuits

Hyperactive enteric glia contribute to persistent dysmotility following inflammation by driving aberrant excitatory responses in neurons

Phosphorylation of Pyruvate Dehydrogenase as a Marker of Neuronal Inactivity in the Enteric Nervous System

The role of the enteric nervous system in the pathogenesis of Clostridioides difficile infection

Endocannabinoids regulate enteric neuron–glia networks and visceral hypersensitivity following inflammation through a glial‐dependent mechanism

Mechanisms of enteric neuropathy in diverse contexts of gastrointestinal dysfunction

Innervation of adipocytes is limited in mouse perivascular adipose tissue

Neuroimmune Connectomes in the Gut and Their Implications in Parkinson’s Disease

The Ties That Bind: Enteric Glia Link T Cells to Plexitis in Crohn’s

Purinergic P2Y1 and P2Y12 receptors control enteric nervous system activity through neuro-glia-macrophage crosstalk

Stimulator of interferon genes (STING) expression in the enteric nervous system and contributions of glial STING in disease

Mini-review: Intercellular communication between enteric glia and neurons

Enteric Neuromics: How High-Throughput “Omics” Deepens Our Understanding of Enteric Nervous System Genetic Architecture

Enteric glia promote visceral hypersensitivity during inflammation through intercellular signaling with gut nociceptors

Sexually Dimorphic Effects of Histamine Degradation by Enteric Glial Histamine N-Methyltransferase (HNMT) on Visceral Hypersensitivity

BQ788 reveals glial ET<sub>B</sub> receptor modulation of neuronal cholinergic and nitrergic pathways to inhibit intestinal motility: Linked to postoperative ileus

Functional Intraregional and Interregional Heterogeneity between Myenteric Glial Cells of the Colon and Duodenum in Mice

Purines help determine the gut’s sweet tooth

LPAR1 regulates enteric nervous system function through glial signaling and contributes to chronic intestinal pseudo-obstruction

Astrocyte Cell Surface Antigen 2 and Other Potential Cell Surface Markers of Enteric glia in the Mouse Colon

Circuit-specific enteric glia regulate intestinal motor neurocircuits

Enteric glial biology, intercellular signalling and roles in gastrointestinal disease

A novel mechanism of rotavirus infection involving purinergic signaling

Collaborators (1)

Stephanie W. Watts

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