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Brian Monk

Associate Professor

University of Otago

New Zealand

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Research Interests

Microbiology

20%

Pharmacology

70%

Chemical Biology

40%

Antifungal Resistance

40%

Antifungal Therapy

30%

Fungal Biology

30%

Antifungal Research

30%

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Articles12

The Molecular Basis of the Intrinsic and Acquired Resistance to Azole Antifungals in Aspergillus fumigatus

Article Link

Year:

2024

Azole Combinations and Multi-Targeting Drugs That Synergistically Inhibit Candidozyma auris

Article Link

Year:

2024

Clorgyline Analogs Synergize with Azoles against Drug Efflux in Candida auris

Article Link

Year:

2023

Functional Expression of Recombinant Candida auris Proteins in Saccharomyces cerevisiae Enables Azole Susceptibility Evaluation and Drug Discovery

Article Link

Year:

2023

Exploring Cryptococcus neoformans CYP51 and Its Cognate Reductase as a Drug Target

Article Link

Year:

2022

Characterisation of Candida parapsilosis CYP51 as a Drug Target Using Saccharomyces cerevisiae as Host

Article Link

Year:

2022

Correction: Monk, B.C.; Keniya, M.V. Roles for Structural Biology in the Discovery of Drugs and Agrochemicals Targeting Sterol 14α-Demethylases. J. Fungi 2021, 7, 67

Article Link

Year:

2021

Structural Insights into the Azole Resistance of the Candida albicans Darlington Strain Using Saccharomyces cerevisiae Lanosterol 14α-Demethylase as a Surrogate

Article Link

Year:

2021

Directed Mutational Strategies Reveal Drug Binding and Transport by the MDR Transporters of Candida albicans

Article Link

Year:

2021

Roles for Structural Biology in the Discovery of Drugs and Agrochemicals Targeting Sterol 14α-Demethylases

Article Link

Year:

2021

Sterol 14α-Demethylase Ligand-Binding Pocket-Mediated Acquired and Intrinsic Azole Resistance in Fungal Pathogens

Article Link

Year:

2020

Dentistry students’ experiences, engagement and perception of biochemistry within the dental curriculum and beyond

Article Link

Year:

2020

Collaborators3

Joel Tyndall

University of Otago

NEW ZEALAND

Lee Ann Adam

Senior Lecturer, Education and Research

University of Otago

NEW ZEALAND

Christoph Müller

Ludwig-Maximilians-Universität München

GERMANY

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Brian Monk

Associate Professor

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Research Interests

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Articles12

The Molecular Basis of the Intrinsic and Acquired Resistance to Azole Antifungals in Aspergillus fumigatus

Azole Combinations and Multi-Targeting Drugs That Synergistically Inhibit <i>Candidozyma auris</i>

Clorgyline Analogs Synergize with Azoles against Drug Efflux in <i>Candida auris</i>

Functional Expression of Recombinant <i>Candida auris</i> Proteins in <i>Saccharomyces cerevisiae </i>Enables Azole Susceptibility Evaluation and Drug Discovery

Exploring <i>Cryptococcus neoformans</i> CYP51 and Its Cognate Reductase as a Drug Target

Characterisation of <i>Candida parapsilosis</i> CYP51 as a Drug Target Using <i>Saccharomyces cerevisiae</i> as Host

Correction: Monk, B.C.; Keniya, M.V. Roles for Structural Biology in the Discovery of Drugs and Agrochemicals Targeting Sterol 14α-Demethylases. <i>J. Fungi</i> 2021, <i>7</i>, 67

Structural Insights into the Azole Resistance of the <i>Candida albicans</i> Darlington Strain Using <i>Saccharomyces cerevisiae</i> Lanosterol 14α-Demethylase as a Surrogate

Directed Mutational Strategies Reveal Drug Binding and Transport by the MDR Transporters of <i>Candida albicans</i>

Roles for Structural Biology in the Discovery of Drugs and Agrochemicals Targeting Sterol 14α-Demethylases

Sterol 14α-Demethylase Ligand-Binding Pocket-Mediated Acquired and Intrinsic Azole Resistance in Fungal Pathogens

Dentistry students’ experiences, engagement and perception of biochemistry within the dental curriculum and beyond

Collaborators3

Joel Tyndall

Lee Ann Adam

Christoph Müller

How do I reach out?

Brian Monk

Associate Professor

How do I reach out?

Contact this professor

Research Interests

Ask ApplyKite AI

Articles12

The Molecular Basis of the Intrinsic and Acquired Resistance to Azole Antifungals in Aspergillus fumigatus

Azole Combinations and Multi-Targeting Drugs That Synergistically Inhibit <i>Candidozyma auris</i>

Clorgyline Analogs Synergize with Azoles against Drug Efflux in <i>Candida auris</i>

Functional Expression of Recombinant <i>Candida auris</i> Proteins in <i>Saccharomyces cerevisiae </i>Enables Azole Susceptibility Evaluation and Drug Discovery

Exploring <i>Cryptococcus neoformans</i> CYP51 and Its Cognate Reductase as a Drug Target

Characterisation of <i>Candida parapsilosis</i> CYP51 as a Drug Target Using <i>Saccharomyces cerevisiae</i> as Host

Correction: Monk, B.C.; Keniya, M.V. Roles for Structural Biology in the Discovery of Drugs and Agrochemicals Targeting Sterol 14&alpha;-Demethylases. <i>J. Fungi</i> 2021, <i>7</i>, 67

Structural Insights into the Azole Resistance of the <i>Candida albicans</i> Darlington Strain Using <i>Saccharomyces cerevisiae</i> Lanosterol 14α-Demethylase as a Surrogate

Directed Mutational Strategies Reveal Drug Binding and Transport by the MDR Transporters of <i>Candida albicans</i>

Roles for Structural Biology in the Discovery of Drugs and Agrochemicals Targeting Sterol 14α-Demethylases

Sterol 14α-Demethylase Ligand-Binding Pocket-Mediated Acquired and Intrinsic Azole Resistance in Fungal Pathogens

Dentistry students’ experiences, engagement and perception of biochemistry within the dental curriculum and beyond

Collaborators3

Joel Tyndall

Lee Ann Adam

Christoph Müller

How do I reach out?

Correction: Monk, B.C.; Keniya, M.V. Roles for Structural Biology in the Discovery of Drugs and Agrochemicals Targeting Sterol 14α-Demethylases. <i>J. Fungi</i> 2021, <i>7</i>, 67