Brian Pfleger

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University of Wisconsin-Madison

United States

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About

Professor Brian Pfleger is a faculty member at the University of Wisconsin Madison in the United States. His research focuses on metabolic engineering, synthetic biology, and the production of biodegradable plastics, with recent articles exploring microbial synthesis of fatty acids and the role of novel proteins in plant colonization. He is dedicated to advancing the field of biotechnology and enhancing microbial applications in various industrial processes.

Recent Grants

Grant: Close

Collaborative Research: SusChEM: Unlocking the fundamental mechanisms that underlie selectivity in oleochemical producing enzymes

Open Date: 2017-09-01

Close Date: 2020-08-31

Grant: Close

An evolutionary approach to enable reprogramming of non-ribosomal peptide enzymology

Open Date: 2017-08-01

Close Date: 2020-07-31

Grant: Close

Application of Next-Generation Sequencing to Engineering mRNA Turnover in Bacteria

Open Date: 2013-07-15

Close Date: 2018-07-14

Grant: Close

EFRI-PSBR: Cyanobacterial Biorefineries

Open Date: 2012-08-15

Close Date: 2018-07-31

Grant: Close

CAREER: Integrating Chemical and Biological Catalysis for the Sustainable Production of Biofuels and Commodity Chemicals

Open Date: 2012-06-01

Close Date: 2018-05-31

Articles (14)

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2025

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2025

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2024

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2023

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2023

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2023

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2023

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2023

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2022

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2022

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2021

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2021

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2021

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2020

Collaborators (4)

Erica Majumder

Assistant Professor

University of Wisconsin-Madison

UNITED STATES

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Jamey D. Young

Vanderbilt University

UNITED STATES

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John A. McLean

Vanderbilt University

UNITED STATES

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Philip Romero

Assistant professor

University of Wisconsin-Madison

UNITED STATES

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Brian Pfleger

Research Interests

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About

Recent Grants

Articles (14)

A metabolic engineering strategy for producing poly-(3-hydroxyoctanoic acid) in Escherichia coli from glycerol

A Novel Membrane-Associated Protein Aids Bacterial Colonization of Maize

Expanding the synthetic biology toolbox of Cupriavidus necator for establishing fatty acid production

A Review of Biodegradable Plastics: Chemistry, Applications, Properties, and Future Research Needs

Milligrams to kilograms: making microbes work at scale

Relative Activities of the β-Ketoacyl-CoA and Acyl-CoA Reductases Influence the Product Profile and Flux in a Reversed β-Oxidation Pathway

Evaluation of strategies to narrow the product chain-length distribution of microbially synthesized free fatty acids

Synthetic Biology Toolbox for Nitrogen-Fixing Soil Microbes

Metabolic engineering strategies to produce medium-chain oleochemicals via acyl-ACP:CoA transacylase activity

Introduction of NADH-dependent nitrate assimilation in Synechococcus sp. PCC 7002 improves photosynthetic production of 2-methyl-1-butanol and isobutanol

Machine learning-guided acyl-ACP reductase engineering for improved in vivo fatty alcohol production

Accelerating strain phenotyping with desorption electrospray ionization-imaging mass spectrometry and untargeted analysis of intact microbial colonies

Optimization of a T7-RNA polymerase system in Synechococcus sp. PCC 7002 mirrors the protein overproduction phenotype from E. coli BL21(DE3)

Corrigendum to “Rewiring yeast metabolism to synthesize products beyond ethanol” [Curr Opin Chem Biol 59 (December 2020) 182–192]

Collaborators (4)

Erica Majumder

Jamey D. Young

John A. McLean

Philip Romero

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