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Bruce Blazar

Regents Professor

University of Minnesota

United States

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Bruce Blazar is a Regents Professor at the University of Minnesota, USA. His research focuses on the prevention and treatment of graft-versus-host disease (GVHD) and cellular therapies, with recent publications addressing topics such as human ILC2 expansion, chronic GVHD, and immunoregulatory mechanisms in autoimmunity. He has contributed significantly to identifying biomarkers and the role of cellular therapies in mitigating acute and chronic complications associated with transplantation.

Articles (20)

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Collaborators (13)

Sanjiv Luther

Full Professor

University of Lausanne

SWITZERLAND

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Xianliang Rui

Staff Scientist

Boston Children's Hospital

UNITED STATES

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Fathima Mohamed

Professionals-in-Training, Professional School Fellow

University of Minnesota

UNITED STATES

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Tomomi Toubai

Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital

JAPAN

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Ulrike Gerdemann

Boston Children's Hospital

UNITED STATES

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Jana Vukovic

Senior Lecturer

University of Queensland

AUSTRALIA

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Steven Lane

LAB HEAD

QIMR Berghofer Medical Research Institute

AUSTRALIA

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Institute of Pharmacology and Structural Biology

FRANCE

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Bruce Blazar

Research Interests

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About

Articles (20)

Regulatory T Cells and Nanomaterials: Dual Perspectives in Therapeutics and Immunomodulation

Belumosudil for Chronic Graft-Versus-Host Disease: Analysis of Long-Term Results from the KD025-208 and ROCKstar Studies

A simple and efficient method for the robust expansion of human ILC2s to prevent acute GVHD

Cellular therapies for the prevention and treatment of acute graft-versus-host disease

Defining pathogenic IL-17 and CSF-1 gene expression signatures in chronic graft-versus-host disease

Immunoregulatory iPSC-derived non-lymphoid progeny in autoimmunity and GVHD alloimmunity

Autophagy prevents graft failure during murine graft-versus-host disease

The Impact of Cell-Intrinsic STAT6 Protein on Donor T Cell-Mediated Graft-Versus-Tumor Effect

Human OX40L–CAR-T regs target activated antigen-presenting cells and control T cell alloreactivity

Chronic graft-versus-host disease: unresolved complication or ancient history?

Validated graft-specific biomarkers identify patients at risk for chronic graft-versus-host disease and death

After Bone Marrow Transplantation, the Cell-Intrinsic Th2 Pathway Promotes Recipient T Lymphocyte Survival and Regulates Graft-versus-Host Disease

IL-33 acts as a costimulatory signal to generate alloreactive Th1 cells in graft-versus-host disease

Clinical response to belumosudil in bronchiolitis obliterans syndrome: a combined analysis from 2 prospective trials

Emerging approaches to improve allogeneic hematopoietic cell transplantation outcomes for nonmalignant diseases

Donor bone marrow–derived macrophage MHC II drives neuroinflammation and altered behavior during chronic GVHD in mice

Analyses and Correlation of Pathologic and Ocular Cutaneous Changes in Murine Graft versus Host Disease

Third-party type 2 innate lymphoid cells prevent and treat GI tract GvHD

Divergent fates of antigen-specific CD8+ T cell clones in mice with acute leukemia

Regulatory T Cell Therapy of Graft-versus-Host Disease: Advances and Challenges

Collaborators (13)

Sanjiv Luther

Xianliang Rui

Fathima Mohamed

Tomomi Toubai

Ulrike Gerdemann

Jana Vukovic

Steven Lane

Stephanie Lee

Mark Kaplan

Jean-Pierre Levesque

Jonathan Serody

Simone Minnie

Anne Gonzalez de Peredo

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